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Need a Wood Lamp Alternative? Grab Your Smartphone

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Practice Gap

The Wood lamp commonly is used as a diagnostic tool for pigmentary skin conditions (eg, vitiligo) or skin conditions that exhibit fluorescence (eg, erythrasma).1 Recently, its diagnostic efficacy has extended to scabies, in which it unveils a distinctive wavy, bluish-white, linear fluorescence upon illumination.2

Functionally, the Wood lamp operates by subjecting phosphors to UV light within the wavelength range of 320 to 400 nm, inducing fluorescence in substances such as collagen and elastin. In the context of vitiligo, this process manifests as a preferential chalk white fluorescence in areas lacking melanin.1

Despite its demonstrated effectiveness, the Wood lamp is not without limitations. It comes with a notable financial investment ranging from $70 to $500, requires periodic maintenance such as light bulb replacements, and can be unwieldy.3 Furthermore, its reliance on a power source poses a challenge in settings where immediate access to convenient power outlets is limited, such as inpatient and rural dermatology clinics. These limitations underscore the need for alternative solutions and innovations to address challenges and ensure accessibility in diverse health care environments.

The Tools

Free smartphone applications (apps), such as Ultraviolet Light-UV Lamp by AppBrain or Blacklight UV Light Simulator by That Smile, can simulate UV light and functionally serve as a Wood lamp.

The Technique

UV light apps use LED or organic LED screen pixels to emit a blue light equivalent at 467 nm.4 Although these apps are not designed specifically for dermatologic uses, they are mostly free, widely available for Android and iPhone users, and portable. Importantly, they can demonstrate good performance in visualizing vitiligo, as shown in Figure 1—albeit perhaps not reaching the same level as the Wood lamp (Figure 2).

FIGURE 1. A and B, Depigmented patches of vitiligo on the skin are visualized with a free UV light smartphone application, respectively.

FIGURE 2. A and B, The same depigmented patches of vitiligo are visualized with a free UV light smartphone application vs a Wood lamp, respectively.

Because these UV light apps are not regulated and their efficacy for medical use has not been firmly established, the Wood lamp remains the gold standard. Therefore, we propose the use of UV light apps in situations when a Wood lamp is not available or convenient, such as in rural, inpatient, or international health care settings.

Practice Implications

Exploring and adopting these free alternatives can contribute to improved accessibility and diagnostic capabilities in diverse health care environments, particularly for communities facing financial constraints. Continued research and validation of these apps in clinical settings will be essential to establish their reliability and effectiveness in enhancing diagnostic practices.

References
  1. Dyer JM, Foy VM. Revealing the unseen: a review of Wood’s lamp in dermatology. J Clin Aesthet Dermatol. 2022;15:25-30.
  2. Scanni G. Facilitations in the clinical diagnosis of human scabies through the use of ultraviolet light (UV-scab scanning): a case-series study. Trop Med Infect Dis. 2022;7:422. doi:10.3390/tropicalmed7120422
  3. USA Medical and Surgical Supplies. Top 9 medical diagnostic applications for a Woods lamp. February 26, 2019. Accessed May 20, 2024.
  4. Huang Y, Hsiang E-L, Deng M-Y, et al. Mini-led, micro-led and OLED displays: present status and future perspectives. Light Sci Appl. 2020;9:105. doi:10.1038/s41377-020-0341-9
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Ruth Zagales is from the Indiana University School of Medicine, Indianapolis. Dr. Korman is from the Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus.

The authors report no conflict of interest.

Correspondence: Abraham M. Korman, MD, 540 Office Center Pl, Ste 240, Columbus, OH 43230 (Abraham.Korman@osumc.edu).

Cutis. 2024 June;113(6):271-272. doi:10.12788/cutis.1026

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Ruth Zagales is from the Indiana University School of Medicine, Indianapolis. Dr. Korman is from the Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus.

The authors report no conflict of interest.

Correspondence: Abraham M. Korman, MD, 540 Office Center Pl, Ste 240, Columbus, OH 43230 (Abraham.Korman@osumc.edu).

Cutis. 2024 June;113(6):271-272. doi:10.12788/cutis.1026

Author and Disclosure Information

 

Ruth Zagales is from the Indiana University School of Medicine, Indianapolis. Dr. Korman is from the Department of Dermatology, The Ohio State University Wexner Medical Center, Columbus.

The authors report no conflict of interest.

Correspondence: Abraham M. Korman, MD, 540 Office Center Pl, Ste 240, Columbus, OH 43230 (Abraham.Korman@osumc.edu).

Cutis. 2024 June;113(6):271-272. doi:10.12788/cutis.1026

Article PDF
Article PDF

Practice Gap

The Wood lamp commonly is used as a diagnostic tool for pigmentary skin conditions (eg, vitiligo) or skin conditions that exhibit fluorescence (eg, erythrasma).1 Recently, its diagnostic efficacy has extended to scabies, in which it unveils a distinctive wavy, bluish-white, linear fluorescence upon illumination.2

Functionally, the Wood lamp operates by subjecting phosphors to UV light within the wavelength range of 320 to 400 nm, inducing fluorescence in substances such as collagen and elastin. In the context of vitiligo, this process manifests as a preferential chalk white fluorescence in areas lacking melanin.1

Despite its demonstrated effectiveness, the Wood lamp is not without limitations. It comes with a notable financial investment ranging from $70 to $500, requires periodic maintenance such as light bulb replacements, and can be unwieldy.3 Furthermore, its reliance on a power source poses a challenge in settings where immediate access to convenient power outlets is limited, such as inpatient and rural dermatology clinics. These limitations underscore the need for alternative solutions and innovations to address challenges and ensure accessibility in diverse health care environments.

The Tools

Free smartphone applications (apps), such as Ultraviolet Light-UV Lamp by AppBrain or Blacklight UV Light Simulator by That Smile, can simulate UV light and functionally serve as a Wood lamp.

The Technique

UV light apps use LED or organic LED screen pixels to emit a blue light equivalent at 467 nm.4 Although these apps are not designed specifically for dermatologic uses, they are mostly free, widely available for Android and iPhone users, and portable. Importantly, they can demonstrate good performance in visualizing vitiligo, as shown in Figure 1—albeit perhaps not reaching the same level as the Wood lamp (Figure 2).

FIGURE 1. A and B, Depigmented patches of vitiligo on the skin are visualized with a free UV light smartphone application, respectively.

FIGURE 2. A and B, The same depigmented patches of vitiligo are visualized with a free UV light smartphone application vs a Wood lamp, respectively.

Because these UV light apps are not regulated and their efficacy for medical use has not been firmly established, the Wood lamp remains the gold standard. Therefore, we propose the use of UV light apps in situations when a Wood lamp is not available or convenient, such as in rural, inpatient, or international health care settings.

Practice Implications

Exploring and adopting these free alternatives can contribute to improved accessibility and diagnostic capabilities in diverse health care environments, particularly for communities facing financial constraints. Continued research and validation of these apps in clinical settings will be essential to establish their reliability and effectiveness in enhancing diagnostic practices.

Practice Gap

The Wood lamp commonly is used as a diagnostic tool for pigmentary skin conditions (eg, vitiligo) or skin conditions that exhibit fluorescence (eg, erythrasma).1 Recently, its diagnostic efficacy has extended to scabies, in which it unveils a distinctive wavy, bluish-white, linear fluorescence upon illumination.2

Functionally, the Wood lamp operates by subjecting phosphors to UV light within the wavelength range of 320 to 400 nm, inducing fluorescence in substances such as collagen and elastin. In the context of vitiligo, this process manifests as a preferential chalk white fluorescence in areas lacking melanin.1

Despite its demonstrated effectiveness, the Wood lamp is not without limitations. It comes with a notable financial investment ranging from $70 to $500, requires periodic maintenance such as light bulb replacements, and can be unwieldy.3 Furthermore, its reliance on a power source poses a challenge in settings where immediate access to convenient power outlets is limited, such as inpatient and rural dermatology clinics. These limitations underscore the need for alternative solutions and innovations to address challenges and ensure accessibility in diverse health care environments.

The Tools

Free smartphone applications (apps), such as Ultraviolet Light-UV Lamp by AppBrain or Blacklight UV Light Simulator by That Smile, can simulate UV light and functionally serve as a Wood lamp.

The Technique

UV light apps use LED or organic LED screen pixels to emit a blue light equivalent at 467 nm.4 Although these apps are not designed specifically for dermatologic uses, they are mostly free, widely available for Android and iPhone users, and portable. Importantly, they can demonstrate good performance in visualizing vitiligo, as shown in Figure 1—albeit perhaps not reaching the same level as the Wood lamp (Figure 2).

FIGURE 1. A and B, Depigmented patches of vitiligo on the skin are visualized with a free UV light smartphone application, respectively.

FIGURE 2. A and B, The same depigmented patches of vitiligo are visualized with a free UV light smartphone application vs a Wood lamp, respectively.

Because these UV light apps are not regulated and their efficacy for medical use has not been firmly established, the Wood lamp remains the gold standard. Therefore, we propose the use of UV light apps in situations when a Wood lamp is not available or convenient, such as in rural, inpatient, or international health care settings.

Practice Implications

Exploring and adopting these free alternatives can contribute to improved accessibility and diagnostic capabilities in diverse health care environments, particularly for communities facing financial constraints. Continued research and validation of these apps in clinical settings will be essential to establish their reliability and effectiveness in enhancing diagnostic practices.

References
  1. Dyer JM, Foy VM. Revealing the unseen: a review of Wood’s lamp in dermatology. J Clin Aesthet Dermatol. 2022;15:25-30.
  2. Scanni G. Facilitations in the clinical diagnosis of human scabies through the use of ultraviolet light (UV-scab scanning): a case-series study. Trop Med Infect Dis. 2022;7:422. doi:10.3390/tropicalmed7120422
  3. USA Medical and Surgical Supplies. Top 9 medical diagnostic applications for a Woods lamp. February 26, 2019. Accessed May 20, 2024.
  4. Huang Y, Hsiang E-L, Deng M-Y, et al. Mini-led, micro-led and OLED displays: present status and future perspectives. Light Sci Appl. 2020;9:105. doi:10.1038/s41377-020-0341-9
References
  1. Dyer JM, Foy VM. Revealing the unseen: a review of Wood’s lamp in dermatology. J Clin Aesthet Dermatol. 2022;15:25-30.
  2. Scanni G. Facilitations in the clinical diagnosis of human scabies through the use of ultraviolet light (UV-scab scanning): a case-series study. Trop Med Infect Dis. 2022;7:422. doi:10.3390/tropicalmed7120422
  3. USA Medical and Surgical Supplies. Top 9 medical diagnostic applications for a Woods lamp. February 26, 2019. Accessed May 20, 2024.
  4. Huang Y, Hsiang E-L, Deng M-Y, et al. Mini-led, micro-led and OLED displays: present status and future perspectives. Light Sci Appl. 2020;9:105. doi:10.1038/s41377-020-0341-9
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A Structured Approach for the Management of Orodynia (Burning Mouth Syndrome)

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Practice Gap

Orodynia (OD)—together with glossodynia colloquially termed “burning mouth syndrome”—is a chronic disorder characterized by a burning sensation within the oral cavity without objective clinical signs. It is most common in perimenopausal and postmenopausal women.1,2

Orodynia is a diagnosis of exclusion and is considered after 4 to 6 months of normal imaging and laboratory test results.1,2 Its pathophysiology is poorly understood, as it can be intermittent or continuous, manifest with a variety of symptoms, and affect various entities of the oral cavity.3,4 The most common structure affected is the tongue, and symptoms may include xerostomia, dysgeusia, and discomfort.1,2 Orodynia is a frustrating condition, as many patients do not respond to treatment and experience symptoms for years.1-4

The current approach to management of OD typically involves a combination of psychosocial strategies and pharmacologic agents. The psychosocial component consists of coping mechanisms (eg, stress management techniques and behavioral therapies) aimed at alleviating the psychological impact of the condition. Pharmacologic agents such as antidepressants, anticonvulsants, and topical medications often are prescribed to address neuropathic pain and dry mouth symptoms.1,2 Additionally, oral rinses, saliva substitutes, and dietary supplements may be recommended to counteract the discomfort associated with xerostomia.1,2 However, there is no stepwise protocol, leaving these treatments to be trialed in a disorganized manner.2

The Tools

In our unique approach to managing OD, physicians may employ a variety of tools, including autoantibody profiles, noninvasive salivary gland analysis, saliva analysis, patch testing for allergens, and—if deemed necessary—a minor salivary gland biopsy. The use of specific prescription medications is included in the later stages of our approach.

The Technique

First, exclude inflammatory conditions such as geographic tongue, oral lichen planus, autoimmune bullous disorders, and other treatable conditions such as dyspepsia and Sjögren syndrome using the tools described above. Noninvasive modalities should be exhausted first, and dermatologists/clinicians should exercise clinical judgement to determine whether all options should be trialed, including more invasive/costly ones.

If symptoms persist, clinicians may want to obtain a culture for oral candida. If results are positive, candida may be treated quickly with oral fluconazole. If that treatment fails and fissuring is present, advise the patient on treating the tongue; we recommend lightly brushing the tongue once daily with a hydrogen peroxide 3% solution, followed by rinsing. Next, the patient can allow an active probiotic yogurt to sit on the tongue for at least 1 minute to repopulate it with healthy oral bacteria.

If symptoms persist, prescribe gabapentin 100 to 300 mg to be taken at bedtime. Cevimeline 30 mg 3 times daily can be added to treat symptoms of xerostomia. As a last resort, a low daily dose of trifluoperazine 1 to 2 mg may alleviate the dysesthesia of OD. Because this medication is an antipsychotic, there is an increased risk for adverse effects such as tardive dyskinesia; however, given that we recommend using at most one-twentieth of the dose recommended for psychiatric illnesses such as schizophrenia, the risk appears to be minimal.5

We have found this protocol to be more structured, and in our practice, it has led to better outcomes than previously described therapeutic interventions.

Practice Implications

As a chronic condition, OD can be frustrating for patients, as many of them have attempted multiple treatments without success. It also may be challenging for dermatologists who are unfamiliar with its management. This approach to OD provides simple step-by-step diagnostic and therapeutic plans for a condition with an often-uncertain etiology and stubborn response to initial treatments. By following this protocol, dermatologists can be confident in their ability to help patients find relief from OD.

References
  1. Klein B, Thoppay JR, De Rossi SS, et al. Burning mouth syndrome. Dermatol Clin. 2020;38:477-483. doi:10.1016/j.det.2020.05.008
  2. Bender SD. Burning mouth syndrome. Dent Clin North Am. 2018;62:585-596. doi:10.1016/j.cden.2018.05.006
  3. Javali MA. Burning mouth syndrome: an enigmatic disorder. Kathmandu Univ Med J. 2013;11:175-178. doi:10.3126/kumj.v11i2.12498
  4. Sardella A, Lodi G, Demarosi F, et al. Burning mouth syndrome: a retrospective study investigating spontaneous remission and response to treatments. Oral Dis. 2006;12:152-155. doi:10.1111/j.1601-0825.2005.01174
  5. Macdonald R, Watts TP. Trifluoperazine dihydrochloride (stelazine) in paranoid schizophrenia. Br Med J. 1959;1:549-550. doi:10.1136/bmj.1.5121.549
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Dane J. Markham is from the Mayo Clinic Alix School of Medicine, Jacksonville, Florida. Taylor S. Davis is from the Saint Louis University School of Medicine, Missouri. Max E. Oscherwitz is from the Heersink School of Medicine, University of Alabama, Birmingham. Dr. Jorizzo is from the Department of Dermatology, Wake Forest University, Winston-Salem, North Carolina.

The authors report no conflict of interest.

Correspondence: Joseph L. Jorizzo, MD, 4618 Country Club Rd, Winston-Salem, NC 27104 (jjorizzo@wakehealth.edu).

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Dane J. Markham is from the Mayo Clinic Alix School of Medicine, Jacksonville, Florida. Taylor S. Davis is from the Saint Louis University School of Medicine, Missouri. Max E. Oscherwitz is from the Heersink School of Medicine, University of Alabama, Birmingham. Dr. Jorizzo is from the Department of Dermatology, Wake Forest University, Winston-Salem, North Carolina.

The authors report no conflict of interest.

Correspondence: Joseph L. Jorizzo, MD, 4618 Country Club Rd, Winston-Salem, NC 27104 (jjorizzo@wakehealth.edu).

Author and Disclosure Information

Dane J. Markham is from the Mayo Clinic Alix School of Medicine, Jacksonville, Florida. Taylor S. Davis is from the Saint Louis University School of Medicine, Missouri. Max E. Oscherwitz is from the Heersink School of Medicine, University of Alabama, Birmingham. Dr. Jorizzo is from the Department of Dermatology, Wake Forest University, Winston-Salem, North Carolina.

The authors report no conflict of interest.

Correspondence: Joseph L. Jorizzo, MD, 4618 Country Club Rd, Winston-Salem, NC 27104 (jjorizzo@wakehealth.edu).

Article PDF
Article PDF

Practice Gap

Orodynia (OD)—together with glossodynia colloquially termed “burning mouth syndrome”—is a chronic disorder characterized by a burning sensation within the oral cavity without objective clinical signs. It is most common in perimenopausal and postmenopausal women.1,2

Orodynia is a diagnosis of exclusion and is considered after 4 to 6 months of normal imaging and laboratory test results.1,2 Its pathophysiology is poorly understood, as it can be intermittent or continuous, manifest with a variety of symptoms, and affect various entities of the oral cavity.3,4 The most common structure affected is the tongue, and symptoms may include xerostomia, dysgeusia, and discomfort.1,2 Orodynia is a frustrating condition, as many patients do not respond to treatment and experience symptoms for years.1-4

The current approach to management of OD typically involves a combination of psychosocial strategies and pharmacologic agents. The psychosocial component consists of coping mechanisms (eg, stress management techniques and behavioral therapies) aimed at alleviating the psychological impact of the condition. Pharmacologic agents such as antidepressants, anticonvulsants, and topical medications often are prescribed to address neuropathic pain and dry mouth symptoms.1,2 Additionally, oral rinses, saliva substitutes, and dietary supplements may be recommended to counteract the discomfort associated with xerostomia.1,2 However, there is no stepwise protocol, leaving these treatments to be trialed in a disorganized manner.2

The Tools

In our unique approach to managing OD, physicians may employ a variety of tools, including autoantibody profiles, noninvasive salivary gland analysis, saliva analysis, patch testing for allergens, and—if deemed necessary—a minor salivary gland biopsy. The use of specific prescription medications is included in the later stages of our approach.

The Technique

First, exclude inflammatory conditions such as geographic tongue, oral lichen planus, autoimmune bullous disorders, and other treatable conditions such as dyspepsia and Sjögren syndrome using the tools described above. Noninvasive modalities should be exhausted first, and dermatologists/clinicians should exercise clinical judgement to determine whether all options should be trialed, including more invasive/costly ones.

If symptoms persist, clinicians may want to obtain a culture for oral candida. If results are positive, candida may be treated quickly with oral fluconazole. If that treatment fails and fissuring is present, advise the patient on treating the tongue; we recommend lightly brushing the tongue once daily with a hydrogen peroxide 3% solution, followed by rinsing. Next, the patient can allow an active probiotic yogurt to sit on the tongue for at least 1 minute to repopulate it with healthy oral bacteria.

If symptoms persist, prescribe gabapentin 100 to 300 mg to be taken at bedtime. Cevimeline 30 mg 3 times daily can be added to treat symptoms of xerostomia. As a last resort, a low daily dose of trifluoperazine 1 to 2 mg may alleviate the dysesthesia of OD. Because this medication is an antipsychotic, there is an increased risk for adverse effects such as tardive dyskinesia; however, given that we recommend using at most one-twentieth of the dose recommended for psychiatric illnesses such as schizophrenia, the risk appears to be minimal.5

We have found this protocol to be more structured, and in our practice, it has led to better outcomes than previously described therapeutic interventions.

Practice Implications

As a chronic condition, OD can be frustrating for patients, as many of them have attempted multiple treatments without success. It also may be challenging for dermatologists who are unfamiliar with its management. This approach to OD provides simple step-by-step diagnostic and therapeutic plans for a condition with an often-uncertain etiology and stubborn response to initial treatments. By following this protocol, dermatologists can be confident in their ability to help patients find relief from OD.

Practice Gap

Orodynia (OD)—together with glossodynia colloquially termed “burning mouth syndrome”—is a chronic disorder characterized by a burning sensation within the oral cavity without objective clinical signs. It is most common in perimenopausal and postmenopausal women.1,2

Orodynia is a diagnosis of exclusion and is considered after 4 to 6 months of normal imaging and laboratory test results.1,2 Its pathophysiology is poorly understood, as it can be intermittent or continuous, manifest with a variety of symptoms, and affect various entities of the oral cavity.3,4 The most common structure affected is the tongue, and symptoms may include xerostomia, dysgeusia, and discomfort.1,2 Orodynia is a frustrating condition, as many patients do not respond to treatment and experience symptoms for years.1-4

The current approach to management of OD typically involves a combination of psychosocial strategies and pharmacologic agents. The psychosocial component consists of coping mechanisms (eg, stress management techniques and behavioral therapies) aimed at alleviating the psychological impact of the condition. Pharmacologic agents such as antidepressants, anticonvulsants, and topical medications often are prescribed to address neuropathic pain and dry mouth symptoms.1,2 Additionally, oral rinses, saliva substitutes, and dietary supplements may be recommended to counteract the discomfort associated with xerostomia.1,2 However, there is no stepwise protocol, leaving these treatments to be trialed in a disorganized manner.2

The Tools

In our unique approach to managing OD, physicians may employ a variety of tools, including autoantibody profiles, noninvasive salivary gland analysis, saliva analysis, patch testing for allergens, and—if deemed necessary—a minor salivary gland biopsy. The use of specific prescription medications is included in the later stages of our approach.

The Technique

First, exclude inflammatory conditions such as geographic tongue, oral lichen planus, autoimmune bullous disorders, and other treatable conditions such as dyspepsia and Sjögren syndrome using the tools described above. Noninvasive modalities should be exhausted first, and dermatologists/clinicians should exercise clinical judgement to determine whether all options should be trialed, including more invasive/costly ones.

If symptoms persist, clinicians may want to obtain a culture for oral candida. If results are positive, candida may be treated quickly with oral fluconazole. If that treatment fails and fissuring is present, advise the patient on treating the tongue; we recommend lightly brushing the tongue once daily with a hydrogen peroxide 3% solution, followed by rinsing. Next, the patient can allow an active probiotic yogurt to sit on the tongue for at least 1 minute to repopulate it with healthy oral bacteria.

If symptoms persist, prescribe gabapentin 100 to 300 mg to be taken at bedtime. Cevimeline 30 mg 3 times daily can be added to treat symptoms of xerostomia. As a last resort, a low daily dose of trifluoperazine 1 to 2 mg may alleviate the dysesthesia of OD. Because this medication is an antipsychotic, there is an increased risk for adverse effects such as tardive dyskinesia; however, given that we recommend using at most one-twentieth of the dose recommended for psychiatric illnesses such as schizophrenia, the risk appears to be minimal.5

We have found this protocol to be more structured, and in our practice, it has led to better outcomes than previously described therapeutic interventions.

Practice Implications

As a chronic condition, OD can be frustrating for patients, as many of them have attempted multiple treatments without success. It also may be challenging for dermatologists who are unfamiliar with its management. This approach to OD provides simple step-by-step diagnostic and therapeutic plans for a condition with an often-uncertain etiology and stubborn response to initial treatments. By following this protocol, dermatologists can be confident in their ability to help patients find relief from OD.

References
  1. Klein B, Thoppay JR, De Rossi SS, et al. Burning mouth syndrome. Dermatol Clin. 2020;38:477-483. doi:10.1016/j.det.2020.05.008
  2. Bender SD. Burning mouth syndrome. Dent Clin North Am. 2018;62:585-596. doi:10.1016/j.cden.2018.05.006
  3. Javali MA. Burning mouth syndrome: an enigmatic disorder. Kathmandu Univ Med J. 2013;11:175-178. doi:10.3126/kumj.v11i2.12498
  4. Sardella A, Lodi G, Demarosi F, et al. Burning mouth syndrome: a retrospective study investigating spontaneous remission and response to treatments. Oral Dis. 2006;12:152-155. doi:10.1111/j.1601-0825.2005.01174
  5. Macdonald R, Watts TP. Trifluoperazine dihydrochloride (stelazine) in paranoid schizophrenia. Br Med J. 1959;1:549-550. doi:10.1136/bmj.1.5121.549
References
  1. Klein B, Thoppay JR, De Rossi SS, et al. Burning mouth syndrome. Dermatol Clin. 2020;38:477-483. doi:10.1016/j.det.2020.05.008
  2. Bender SD. Burning mouth syndrome. Dent Clin North Am. 2018;62:585-596. doi:10.1016/j.cden.2018.05.006
  3. Javali MA. Burning mouth syndrome: an enigmatic disorder. Kathmandu Univ Med J. 2013;11:175-178. doi:10.3126/kumj.v11i2.12498
  4. Sardella A, Lodi G, Demarosi F, et al. Burning mouth syndrome: a retrospective study investigating spontaneous remission and response to treatments. Oral Dis. 2006;12:152-155. doi:10.1111/j.1601-0825.2005.01174
  5. Macdonald R, Watts TP. Trifluoperazine dihydrochloride (stelazine) in paranoid schizophrenia. Br Med J. 1959;1:549-550. doi:10.1136/bmj.1.5121.549
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Enhancing Cosmetic and Functional Improvement of Recalcitrant Nail Lichen Planus With Resin Nail

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Practice Gap

Lichen planus (LP)—a chronic inflammatory disorder affecting the nails—is prevalent in 10% to 15% of patients and is more common in the fingernails than toenails. Clinical manifestation includes longitudinal ridges, nail plate atrophy, and splitting, which all contribute to cosmetic disfigurement and difficulty with functionality. Quality of life and daily activities may be impacted profoundly.1 First-line therapies include intralesional and systemic corticosteroids; however, efficacy is limited and recurrence is common.1,2 Lichen planus is one of the few conditions that may cause permanent and debilitating nail loss.

Tools

A resin nail can be used to improve cosmetic appearance and functionality in patients with recalcitrant nail LP. The composite resin creates a flexible nonporous nail and allows the underlying natural nail to grow. Application of resin nails has been used for toenail onychodystrophies to improve cosmesis and functionality but has not been reported for fingernails. The resin typically lasts 6 to 8 weeks on toenails.

 

The Technique

Application of a resin nail involves several steps (see video online). First, the affected nail should be debrided and a bonding agent applied. Next, multiple layers of resin are applied until the patient’s desired thickness is achieved (typically 2 layers), followed by a sealing agent. Finally, the nail is cured with UV light. We recommend applying sunscreen to the hand(s) prior to curing with UV light. The liquid resin allows the nail to be customized to the patient’s desired length and shape. The overall procedure takes approximately 20 minutes for a single nail.

We applied resin nail to the thumbnail of a 46-year-old woman with recalcitrant isolated nail LP of 7 years’ duration (Figure). She previously had difficulties performing everyday activities, and the resin improved her functionality. She also was pleased with the cosmetic appearance. After 2 weeks, the resin started falling off with corresponding natural nail growth. The patient denied any adverse events.

A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.
A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.

Practice Implications

Resin nail application may serve as a temporary solution to improve cosmesis and functionality in patients with recalcitrant nail LP. As shown in our patient, the resin may fall off faster on the fingernails than the toenails, likely because of the faster growth rate of fingernails and more frequent exposure from daily activities. Further studies of resin nail application for the fingernails are needed to establish duration in patients with varying levels of activity (eg, washing dishes, woodworking).

Because the resin nail may be removed easily at any time, resin nail application does not interfere with treatments such as intralesional steroid injections. For patients using a topical medication regimen, the resin nail may be applied slightly distal to the cuticle so that the medication can still be applied by the proximal nail fold of the underlying natural nail.

The resin nail should be kept short and removed after 2 to 4 weeks for the fingernails and 6 to 8 weeks for the toenails to examine the underlying natural nail. Patients may go about their daily activities with the resin nail, including applying nail polish to the resin nail, bathing, and swimming. Resin nail application may complement medical treatments and improve quality of life for patients with nail LP.

References
  1. Gupta MK, Lipner SR. Review of nail lichen planus: epidemiology, pathogenesis, diagnosis, and treatment. Dermatol Clin. 2021;39:221-230. doi:10.1016/j.det.2020.12.002
  2. Iorizzo M, Tosti A, Starace M, et al. Isolated nail lichen planus: an expert consensus on treatment of the classical form. J Am Acad Dermatol. 2020;83:1717-1723. doi:10.1016/j.jaad.2020.02.056
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Kaya L. Curtis is from Weill Cornell Medical College, New York, NY. Drs. Ricardo and Lipner are from the Department of Dermatology, Weill Cornell Medicine, New York, NY.

Kaya L. Curtis and Dr. Richard report no conflicts of interest. Dr. Lipner has served as a consultant for BelleTorus Corporation, Eli Lilly and Company, Moberg Pharmaceuticals, and Ortho-Dermatologics.

The video is available online at www.mdedge.com/dermatology.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 (shl9032@med.cornell.edu).

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Kaya L. Curtis is from Weill Cornell Medical College, New York, NY. Drs. Ricardo and Lipner are from the Department of Dermatology, Weill Cornell Medicine, New York, NY.

Kaya L. Curtis and Dr. Richard report no conflicts of interest. Dr. Lipner has served as a consultant for BelleTorus Corporation, Eli Lilly and Company, Moberg Pharmaceuticals, and Ortho-Dermatologics.

The video is available online at www.mdedge.com/dermatology.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 (shl9032@med.cornell.edu).

Author and Disclosure Information

Kaya L. Curtis is from Weill Cornell Medical College, New York, NY. Drs. Ricardo and Lipner are from the Department of Dermatology, Weill Cornell Medicine, New York, NY.

Kaya L. Curtis and Dr. Richard report no conflicts of interest. Dr. Lipner has served as a consultant for BelleTorus Corporation, Eli Lilly and Company, Moberg Pharmaceuticals, and Ortho-Dermatologics.

The video is available online at www.mdedge.com/dermatology.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 (shl9032@med.cornell.edu).

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Practice Gap

Lichen planus (LP)—a chronic inflammatory disorder affecting the nails—is prevalent in 10% to 15% of patients and is more common in the fingernails than toenails. Clinical manifestation includes longitudinal ridges, nail plate atrophy, and splitting, which all contribute to cosmetic disfigurement and difficulty with functionality. Quality of life and daily activities may be impacted profoundly.1 First-line therapies include intralesional and systemic corticosteroids; however, efficacy is limited and recurrence is common.1,2 Lichen planus is one of the few conditions that may cause permanent and debilitating nail loss.

Tools

A resin nail can be used to improve cosmetic appearance and functionality in patients with recalcitrant nail LP. The composite resin creates a flexible nonporous nail and allows the underlying natural nail to grow. Application of resin nails has been used for toenail onychodystrophies to improve cosmesis and functionality but has not been reported for fingernails. The resin typically lasts 6 to 8 weeks on toenails.

 

The Technique

Application of a resin nail involves several steps (see video online). First, the affected nail should be debrided and a bonding agent applied. Next, multiple layers of resin are applied until the patient’s desired thickness is achieved (typically 2 layers), followed by a sealing agent. Finally, the nail is cured with UV light. We recommend applying sunscreen to the hand(s) prior to curing with UV light. The liquid resin allows the nail to be customized to the patient’s desired length and shape. The overall procedure takes approximately 20 minutes for a single nail.

We applied resin nail to the thumbnail of a 46-year-old woman with recalcitrant isolated nail LP of 7 years’ duration (Figure). She previously had difficulties performing everyday activities, and the resin improved her functionality. She also was pleased with the cosmetic appearance. After 2 weeks, the resin started falling off with corresponding natural nail growth. The patient denied any adverse events.

A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.
A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.

Practice Implications

Resin nail application may serve as a temporary solution to improve cosmesis and functionality in patients with recalcitrant nail LP. As shown in our patient, the resin may fall off faster on the fingernails than the toenails, likely because of the faster growth rate of fingernails and more frequent exposure from daily activities. Further studies of resin nail application for the fingernails are needed to establish duration in patients with varying levels of activity (eg, washing dishes, woodworking).

Because the resin nail may be removed easily at any time, resin nail application does not interfere with treatments such as intralesional steroid injections. For patients using a topical medication regimen, the resin nail may be applied slightly distal to the cuticle so that the medication can still be applied by the proximal nail fold of the underlying natural nail.

The resin nail should be kept short and removed after 2 to 4 weeks for the fingernails and 6 to 8 weeks for the toenails to examine the underlying natural nail. Patients may go about their daily activities with the resin nail, including applying nail polish to the resin nail, bathing, and swimming. Resin nail application may complement medical treatments and improve quality of life for patients with nail LP.

Practice Gap

Lichen planus (LP)—a chronic inflammatory disorder affecting the nails—is prevalent in 10% to 15% of patients and is more common in the fingernails than toenails. Clinical manifestation includes longitudinal ridges, nail plate atrophy, and splitting, which all contribute to cosmetic disfigurement and difficulty with functionality. Quality of life and daily activities may be impacted profoundly.1 First-line therapies include intralesional and systemic corticosteroids; however, efficacy is limited and recurrence is common.1,2 Lichen planus is one of the few conditions that may cause permanent and debilitating nail loss.

Tools

A resin nail can be used to improve cosmetic appearance and functionality in patients with recalcitrant nail LP. The composite resin creates a flexible nonporous nail and allows the underlying natural nail to grow. Application of resin nails has been used for toenail onychodystrophies to improve cosmesis and functionality but has not been reported for fingernails. The resin typically lasts 6 to 8 weeks on toenails.

 

The Technique

Application of a resin nail involves several steps (see video online). First, the affected nail should be debrided and a bonding agent applied. Next, multiple layers of resin are applied until the patient’s desired thickness is achieved (typically 2 layers), followed by a sealing agent. Finally, the nail is cured with UV light. We recommend applying sunscreen to the hand(s) prior to curing with UV light. The liquid resin allows the nail to be customized to the patient’s desired length and shape. The overall procedure takes approximately 20 minutes for a single nail.

We applied resin nail to the thumbnail of a 46-year-old woman with recalcitrant isolated nail LP of 7 years’ duration (Figure). She previously had difficulties performing everyday activities, and the resin improved her functionality. She also was pleased with the cosmetic appearance. After 2 weeks, the resin started falling off with corresponding natural nail growth. The patient denied any adverse events.

A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.
A, Lichen planus of the thumbnail before application of resin nail. B, Fingernail after application of resin nail.

Practice Implications

Resin nail application may serve as a temporary solution to improve cosmesis and functionality in patients with recalcitrant nail LP. As shown in our patient, the resin may fall off faster on the fingernails than the toenails, likely because of the faster growth rate of fingernails and more frequent exposure from daily activities. Further studies of resin nail application for the fingernails are needed to establish duration in patients with varying levels of activity (eg, washing dishes, woodworking).

Because the resin nail may be removed easily at any time, resin nail application does not interfere with treatments such as intralesional steroid injections. For patients using a topical medication regimen, the resin nail may be applied slightly distal to the cuticle so that the medication can still be applied by the proximal nail fold of the underlying natural nail.

The resin nail should be kept short and removed after 2 to 4 weeks for the fingernails and 6 to 8 weeks for the toenails to examine the underlying natural nail. Patients may go about their daily activities with the resin nail, including applying nail polish to the resin nail, bathing, and swimming. Resin nail application may complement medical treatments and improve quality of life for patients with nail LP.

References
  1. Gupta MK, Lipner SR. Review of nail lichen planus: epidemiology, pathogenesis, diagnosis, and treatment. Dermatol Clin. 2021;39:221-230. doi:10.1016/j.det.2020.12.002
  2. Iorizzo M, Tosti A, Starace M, et al. Isolated nail lichen planus: an expert consensus on treatment of the classical form. J Am Acad Dermatol. 2020;83:1717-1723. doi:10.1016/j.jaad.2020.02.056
References
  1. Gupta MK, Lipner SR. Review of nail lichen planus: epidemiology, pathogenesis, diagnosis, and treatment. Dermatol Clin. 2021;39:221-230. doi:10.1016/j.det.2020.12.002
  2. Iorizzo M, Tosti A, Starace M, et al. Isolated nail lichen planus: an expert consensus on treatment of the classical form. J Am Acad Dermatol. 2020;83:1717-1723. doi:10.1016/j.jaad.2020.02.056
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How to Optimize Epidermal Approximation During Wound Suturing Using a Smartphone Camera

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Practice Gap

Precise wound approximation during cutaneous suturing is of vital importance for optimal closure and long-term scar outcomes. Although buried dermal sutures achieve wound-edge approximation and eversion, meticulous placement of epidermal sutures allows for fine-tuning of the wound edges through epidermal approximation, eversion, and the correction of minor height discrepancies (step-offs).

Several percutaneous suture techniques and materials are available to dermatologic surgeons. However, precise, gap- and tension-free approximation of the wound edges is desired for prompt re-epithelialization and a barely visible scar.1,2

Epidermal sutures should be placed under minimal tension to align the papillary dermis and epidermis precisely. The dermatologic surgeon can evaluate the effectiveness of their suturing technique by carefully examining the closure for visibility of the bilateral wound edges, which should show equally if approximation is precise; small gaps between the wound edges (undesired); or dermal bleeding, which is a manifestation of inaccurate approximation.

Advances in smartphone camera technology have led to high-quality photography in a variety of settings. Although smartphone photography often is used for documentation purposes in health care, we recommend incorporating it as a quality-control checkpoint for objective evaluation, allowing the dermatologic surgeon to scrutinize the wound edges and refine their surgical technique to improve scar outcomes.

The Technique

After suturing the wound closed, we routinely use a 12-megapixel smartphone camera (up to 2× optical zoom) to photograph the closed wound at 1× or 2× magnification to capture more details and use the zoom function to further evaluate the wound edges close-up (Figure). In any area where inadequate epidermal approximation is noted on the photograph, an additional stitch can be placed. Photography can be repeated until ideal reapproximation occurs.

Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera.
Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera. A, The inferior aspect of the wound was not approximated perfectly, as evidenced by a thin line of blood between the 2 edges. B, Placement of a cross-stitch resulted in perfect epidermal approximation and eversion.

Practice Implications

Most smartphones released in recent years have a 12-megapixel camera, making them more easily accessible than surgical loupes. Additionally, surgical loupes are expensive, come with a learning curve, and can be intimidating to new or inexperienced surgeons or dermatology residents. Because virtually every dermatologic surgeon has access to a smartphone and snapping an image takes no more than a few seconds, we believe this technique is a valuable new self-assessment tool for dermatologic surgeons. It may be particularly valuable to dermatology residents and new/inexperienced surgeons looking to improve their techniques and scar outcomes.

References
  1. Perry AW, McShane RH. Fine-tuning of the skin edges in the closure of surgical wounds. Controlling inversion and eversion with the path of the needle—the right stitch at the right time. J Dermatol Surg Oncol. 1981;7:471-476. doi:10.1111/j.1524-4725.1981.tb00680.x
  2. Miller CJ, Antunes MB, Sobanko JF. Surgical technique for optimal outcomes: part II. repairing tissue: suturing. J Am Acad Dermatol. 2015;72:389-402. doi:10.1016/j.jaad.2014.08.006
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From the Division of Dermatology, Houston Methodist Hospital, Texas, and DermSurgery Associates, Houston.

The authors report on conflict of interest.

Correspondence: Leonard H. Goldberg, MD, DermSurgery Associates, 7515 S Main St, Ste 240, Houston, TX 77030 (goldb1@dermsurgery.org).

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Correspondence: Leonard H. Goldberg, MD, DermSurgery Associates, 7515 S Main St, Ste 240, Houston, TX 77030 (goldb1@dermsurgery.org).

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From the Division of Dermatology, Houston Methodist Hospital, Texas, and DermSurgery Associates, Houston.

The authors report on conflict of interest.

Correspondence: Leonard H. Goldberg, MD, DermSurgery Associates, 7515 S Main St, Ste 240, Houston, TX 77030 (goldb1@dermsurgery.org).

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Practice Gap

Precise wound approximation during cutaneous suturing is of vital importance for optimal closure and long-term scar outcomes. Although buried dermal sutures achieve wound-edge approximation and eversion, meticulous placement of epidermal sutures allows for fine-tuning of the wound edges through epidermal approximation, eversion, and the correction of minor height discrepancies (step-offs).

Several percutaneous suture techniques and materials are available to dermatologic surgeons. However, precise, gap- and tension-free approximation of the wound edges is desired for prompt re-epithelialization and a barely visible scar.1,2

Epidermal sutures should be placed under minimal tension to align the papillary dermis and epidermis precisely. The dermatologic surgeon can evaluate the effectiveness of their suturing technique by carefully examining the closure for visibility of the bilateral wound edges, which should show equally if approximation is precise; small gaps between the wound edges (undesired); or dermal bleeding, which is a manifestation of inaccurate approximation.

Advances in smartphone camera technology have led to high-quality photography in a variety of settings. Although smartphone photography often is used for documentation purposes in health care, we recommend incorporating it as a quality-control checkpoint for objective evaluation, allowing the dermatologic surgeon to scrutinize the wound edges and refine their surgical technique to improve scar outcomes.

The Technique

After suturing the wound closed, we routinely use a 12-megapixel smartphone camera (up to 2× optical zoom) to photograph the closed wound at 1× or 2× magnification to capture more details and use the zoom function to further evaluate the wound edges close-up (Figure). In any area where inadequate epidermal approximation is noted on the photograph, an additional stitch can be placed. Photography can be repeated until ideal reapproximation occurs.

Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera.
Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera. A, The inferior aspect of the wound was not approximated perfectly, as evidenced by a thin line of blood between the 2 edges. B, Placement of a cross-stitch resulted in perfect epidermal approximation and eversion.

Practice Implications

Most smartphones released in recent years have a 12-megapixel camera, making them more easily accessible than surgical loupes. Additionally, surgical loupes are expensive, come with a learning curve, and can be intimidating to new or inexperienced surgeons or dermatology residents. Because virtually every dermatologic surgeon has access to a smartphone and snapping an image takes no more than a few seconds, we believe this technique is a valuable new self-assessment tool for dermatologic surgeons. It may be particularly valuable to dermatology residents and new/inexperienced surgeons looking to improve their techniques and scar outcomes.

Practice Gap

Precise wound approximation during cutaneous suturing is of vital importance for optimal closure and long-term scar outcomes. Although buried dermal sutures achieve wound-edge approximation and eversion, meticulous placement of epidermal sutures allows for fine-tuning of the wound edges through epidermal approximation, eversion, and the correction of minor height discrepancies (step-offs).

Several percutaneous suture techniques and materials are available to dermatologic surgeons. However, precise, gap- and tension-free approximation of the wound edges is desired for prompt re-epithelialization and a barely visible scar.1,2

Epidermal sutures should be placed under minimal tension to align the papillary dermis and epidermis precisely. The dermatologic surgeon can evaluate the effectiveness of their suturing technique by carefully examining the closure for visibility of the bilateral wound edges, which should show equally if approximation is precise; small gaps between the wound edges (undesired); or dermal bleeding, which is a manifestation of inaccurate approximation.

Advances in smartphone camera technology have led to high-quality photography in a variety of settings. Although smartphone photography often is used for documentation purposes in health care, we recommend incorporating it as a quality-control checkpoint for objective evaluation, allowing the dermatologic surgeon to scrutinize the wound edges and refine their surgical technique to improve scar outcomes.

The Technique

After suturing the wound closed, we routinely use a 12-megapixel smartphone camera (up to 2× optical zoom) to photograph the closed wound at 1× or 2× magnification to capture more details and use the zoom function to further evaluate the wound edges close-up (Figure). In any area where inadequate epidermal approximation is noted on the photograph, an additional stitch can be placed. Photography can be repeated until ideal reapproximation occurs.

Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera.
Postoperative wound edge with 5-0 nylon sutures photographed using a 12-megapixel smartphone camera. A, The inferior aspect of the wound was not approximated perfectly, as evidenced by a thin line of blood between the 2 edges. B, Placement of a cross-stitch resulted in perfect epidermal approximation and eversion.

Practice Implications

Most smartphones released in recent years have a 12-megapixel camera, making them more easily accessible than surgical loupes. Additionally, surgical loupes are expensive, come with a learning curve, and can be intimidating to new or inexperienced surgeons or dermatology residents. Because virtually every dermatologic surgeon has access to a smartphone and snapping an image takes no more than a few seconds, we believe this technique is a valuable new self-assessment tool for dermatologic surgeons. It may be particularly valuable to dermatology residents and new/inexperienced surgeons looking to improve their techniques and scar outcomes.

References
  1. Perry AW, McShane RH. Fine-tuning of the skin edges in the closure of surgical wounds. Controlling inversion and eversion with the path of the needle—the right stitch at the right time. J Dermatol Surg Oncol. 1981;7:471-476. doi:10.1111/j.1524-4725.1981.tb00680.x
  2. Miller CJ, Antunes MB, Sobanko JF. Surgical technique for optimal outcomes: part II. repairing tissue: suturing. J Am Acad Dermatol. 2015;72:389-402. doi:10.1016/j.jaad.2014.08.006
References
  1. Perry AW, McShane RH. Fine-tuning of the skin edges in the closure of surgical wounds. Controlling inversion and eversion with the path of the needle—the right stitch at the right time. J Dermatol Surg Oncol. 1981;7:471-476. doi:10.1111/j.1524-4725.1981.tb00680.x
  2. Miller CJ, Antunes MB, Sobanko JF. Surgical technique for optimal outcomes: part II. repairing tissue: suturing. J Am Acad Dermatol. 2015;72:389-402. doi:10.1016/j.jaad.2014.08.006
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Punch Biopsy Extraction With Fingers

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Practice Gap

Punch biopsies are utilized frequently by dermatologists to aid in the diagnosis of various skin diseases.1 When performing a punch biopsy, dermatologists are taught to use either forceps or skin hooks in addition to scissors to extract the tissue from the skin.2 However, the use of these sterile instruments for a simple biopsy adds extra costs to the procedure. Herein, a cheaper and often faster method of obtaining the specimen from the patient is described.

The Technique

A 3- or 4-mm disposable punch biopsy tool is employed for this method. After locally anesthetizing the skin, the skin is punched to a subcutaneous depth utilizing the full length of the blade and a little extra pressure is applied downward while stretching the skin around (Figure, A). This may be helpful to dislodge the punch specimen from the surrounding skin. The specimen now can be easily removed by gently grasping it with the thumb and index finger (Figure, B and C). It then can be transferred immediately to the formalin container.

A, Using this technique, extra downward pressure is applied while the skin is stretched during the punch biopsy. B, The specimen is grasped with the thumb and index finger. C, The removed specimen can then be transferred to a formalin container.

Practice Implications

This technique saves time as well as financial and environmental costs associated with the use of sterile instruments. An additional advantage to this simple method is avoiding specimen crush injuries, which are common when using forceps. This solution works in most cases but may not be suitable for certain special anatomic locations such as the scalp, nose, and ears.

References
  1. Gronbeck C, Feng H. Volume and distribution of skin biopsies performed by dermatologists and other health care providers in the Medicare population in 2019. J Am Acad Dermatol. 2022;87:675-678.
  2. Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier; 2018.
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Practice Gap

Punch biopsies are utilized frequently by dermatologists to aid in the diagnosis of various skin diseases.1 When performing a punch biopsy, dermatologists are taught to use either forceps or skin hooks in addition to scissors to extract the tissue from the skin.2 However, the use of these sterile instruments for a simple biopsy adds extra costs to the procedure. Herein, a cheaper and often faster method of obtaining the specimen from the patient is described.

The Technique

A 3- or 4-mm disposable punch biopsy tool is employed for this method. After locally anesthetizing the skin, the skin is punched to a subcutaneous depth utilizing the full length of the blade and a little extra pressure is applied downward while stretching the skin around (Figure, A). This may be helpful to dislodge the punch specimen from the surrounding skin. The specimen now can be easily removed by gently grasping it with the thumb and index finger (Figure, B and C). It then can be transferred immediately to the formalin container.

A, Using this technique, extra downward pressure is applied while the skin is stretched during the punch biopsy. B, The specimen is grasped with the thumb and index finger. C, The removed specimen can then be transferred to a formalin container.

Practice Implications

This technique saves time as well as financial and environmental costs associated with the use of sterile instruments. An additional advantage to this simple method is avoiding specimen crush injuries, which are common when using forceps. This solution works in most cases but may not be suitable for certain special anatomic locations such as the scalp, nose, and ears.

Practice Gap

Punch biopsies are utilized frequently by dermatologists to aid in the diagnosis of various skin diseases.1 When performing a punch biopsy, dermatologists are taught to use either forceps or skin hooks in addition to scissors to extract the tissue from the skin.2 However, the use of these sterile instruments for a simple biopsy adds extra costs to the procedure. Herein, a cheaper and often faster method of obtaining the specimen from the patient is described.

The Technique

A 3- or 4-mm disposable punch biopsy tool is employed for this method. After locally anesthetizing the skin, the skin is punched to a subcutaneous depth utilizing the full length of the blade and a little extra pressure is applied downward while stretching the skin around (Figure, A). This may be helpful to dislodge the punch specimen from the surrounding skin. The specimen now can be easily removed by gently grasping it with the thumb and index finger (Figure, B and C). It then can be transferred immediately to the formalin container.

A, Using this technique, extra downward pressure is applied while the skin is stretched during the punch biopsy. B, The specimen is grasped with the thumb and index finger. C, The removed specimen can then be transferred to a formalin container.

Practice Implications

This technique saves time as well as financial and environmental costs associated with the use of sterile instruments. An additional advantage to this simple method is avoiding specimen crush injuries, which are common when using forceps. This solution works in most cases but may not be suitable for certain special anatomic locations such as the scalp, nose, and ears.

References
  1. Gronbeck C, Feng H. Volume and distribution of skin biopsies performed by dermatologists and other health care providers in the Medicare population in 2019. J Am Acad Dermatol. 2022;87:675-678.
  2. Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier; 2018.
References
  1. Gronbeck C, Feng H. Volume and distribution of skin biopsies performed by dermatologists and other health care providers in the Medicare population in 2019. J Am Acad Dermatol. 2022;87:675-678.
  2. Bolognia JL, Schaffer JV, Cerroni L. Dermatology. Elsevier; 2018.
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The Many Uses of the Humble Alcohol Swab

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Practice Gap

In light of inflation, rising costs of procedures, and decreased reimbursements,1 there is an increased need to identify and utilize inexpensive multitasking tools that can serve the dermatologic surgeon from preoperative to postoperative care. The 70% isopropyl alcohol swab may be the dermatologist’s most cost-effective and versatile surgical tool.

The Technique

When assessing a lesion, alcohol swabs can remove scale, crust, or residue from personal care products to help reveal primary morphology. They aid in the diagnosis of porokeratosis by highlighting the cornoid lamella when used following application of gentian violet.2 The alcohol swab also can lay down a liquid interface to facilitate contact dermoscopy and improve visualization while also reducing the transmission of pathogens by the dermatoscope.3 Rubbing an area with an alcohol swab can induce vasodilation of scar tissue, which also may help localize a prior biopsy or surgical site (Figure).

A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.
A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.

Before a surgical site is marked, an initial cleanse with an alcohol swab serves to both remove debris and provide antisepsis ahead of the procedure. Additionally, the swab may improve adherence of skin markers by clearing excess lipid from the skin surface. Assessing the amount of debris and oil removed in the process can help determine a patient’s baseline level of hygiene, which can aid postoperative wound care planning. In extreme cases, use of an alcohol swab may help diagnose dermatitis neglecta or terra firma-forme dermatosis by completely removing any pigmentation.4 

After surgery, the alcohol swab can remove skin marker(s) and blood and prepare the site for the surgical dressing. There also is some evidence to suggest that cleansing the surgical site with an alcohol swab as part of routine postoperative wound care may decrease incidence of surgical-site infection.5 At follow-up, the swab can remove crust and clean the skin before suture removal. If infection is suspected, the swab can cleanse skin before a wound culture is obtained to remove skin commensals and flora on the outer surface of the wound.

Practice Implications

The 70% isopropyl alcohol swab can assist the dermatologist in numerous tasks related to everyday procedures. It is readily available in every clinic and costs only a few cents.

References
  1. Pollock JR, Chen JY, Dorius DA, et al. Decreasing physician Medicare reimbursement for dermatology services. J Am Acad Dermatol. 2022;86:1154-1156.
  2. Thomas CJ, Elston DM. Medical pearl: Gentian violet to highlight the cornoid lamella in disseminated superficial actinic porokeratosis.J Am Acad Dermatol. 2005;52(3 pt 1):513-514.
  3. Kelly SC, Purcell SM. Prevention of nosocomial infection during dermoscopy? Dermatol Surg. 2006;32:552-555.
  4. Blattner CM, Perry B, Snider K, et al. Clinical pearl: increasing utility of isopropyl alcohol for cutaneous dyschromia. Cutis. 2016;97:287;301.
  5. Vogt KN, Chadi S, Parry N, et al. Daily incision cleansing with alcohol reduces the rate of surgical site infections: a pilot study. Am Surg. 2015;81:1182-1186.
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Drs. Nathan and Tiger are from the Department of Dermatology, Lahey Health and Medical Center, Peabody, Massachusetts. Dr. O’Connor is from Dermatology and Skin Health, Dover, New Hampshire.

The authors report no conflict of interest.

Correspondence: Jeffrey B. Tiger, MD, Lahey Health and Medical Center, Peabody, One Essex Center Dr, Peabody, MA 01960 (jeffrey.b.tiger@lahey.org).

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Correspondence: Jeffrey B. Tiger, MD, Lahey Health and Medical Center, Peabody, One Essex Center Dr, Peabody, MA 01960 (jeffrey.b.tiger@lahey.org).

Author and Disclosure Information

Drs. Nathan and Tiger are from the Department of Dermatology, Lahey Health and Medical Center, Peabody, Massachusetts. Dr. O’Connor is from Dermatology and Skin Health, Dover, New Hampshire.

The authors report no conflict of interest.

Correspondence: Jeffrey B. Tiger, MD, Lahey Health and Medical Center, Peabody, One Essex Center Dr, Peabody, MA 01960 (jeffrey.b.tiger@lahey.org).

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Practice Gap

In light of inflation, rising costs of procedures, and decreased reimbursements,1 there is an increased need to identify and utilize inexpensive multitasking tools that can serve the dermatologic surgeon from preoperative to postoperative care. The 70% isopropyl alcohol swab may be the dermatologist’s most cost-effective and versatile surgical tool.

The Technique

When assessing a lesion, alcohol swabs can remove scale, crust, or residue from personal care products to help reveal primary morphology. They aid in the diagnosis of porokeratosis by highlighting the cornoid lamella when used following application of gentian violet.2 The alcohol swab also can lay down a liquid interface to facilitate contact dermoscopy and improve visualization while also reducing the transmission of pathogens by the dermatoscope.3 Rubbing an area with an alcohol swab can induce vasodilation of scar tissue, which also may help localize a prior biopsy or surgical site (Figure).

A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.
A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.

Before a surgical site is marked, an initial cleanse with an alcohol swab serves to both remove debris and provide antisepsis ahead of the procedure. Additionally, the swab may improve adherence of skin markers by clearing excess lipid from the skin surface. Assessing the amount of debris and oil removed in the process can help determine a patient’s baseline level of hygiene, which can aid postoperative wound care planning. In extreme cases, use of an alcohol swab may help diagnose dermatitis neglecta or terra firma-forme dermatosis by completely removing any pigmentation.4 

After surgery, the alcohol swab can remove skin marker(s) and blood and prepare the site for the surgical dressing. There also is some evidence to suggest that cleansing the surgical site with an alcohol swab as part of routine postoperative wound care may decrease incidence of surgical-site infection.5 At follow-up, the swab can remove crust and clean the skin before suture removal. If infection is suspected, the swab can cleanse skin before a wound culture is obtained to remove skin commensals and flora on the outer surface of the wound.

Practice Implications

The 70% isopropyl alcohol swab can assist the dermatologist in numerous tasks related to everyday procedures. It is readily available in every clinic and costs only a few cents.

Practice Gap

In light of inflation, rising costs of procedures, and decreased reimbursements,1 there is an increased need to identify and utilize inexpensive multitasking tools that can serve the dermatologic surgeon from preoperative to postoperative care. The 70% isopropyl alcohol swab may be the dermatologist’s most cost-effective and versatile surgical tool.

The Technique

When assessing a lesion, alcohol swabs can remove scale, crust, or residue from personal care products to help reveal primary morphology. They aid in the diagnosis of porokeratosis by highlighting the cornoid lamella when used following application of gentian violet.2 The alcohol swab also can lay down a liquid interface to facilitate contact dermoscopy and improve visualization while also reducing the transmission of pathogens by the dermatoscope.3 Rubbing an area with an alcohol swab can induce vasodilation of scar tissue, which also may help localize a prior biopsy or surgical site (Figure).

A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.
A, An ill-defined biopsy scar on the upper arm. B, Rubbing it with an alcohol swab showed blushing, which facilitated accurate identification via dermoscopy or plain visualization.

Before a surgical site is marked, an initial cleanse with an alcohol swab serves to both remove debris and provide antisepsis ahead of the procedure. Additionally, the swab may improve adherence of skin markers by clearing excess lipid from the skin surface. Assessing the amount of debris and oil removed in the process can help determine a patient’s baseline level of hygiene, which can aid postoperative wound care planning. In extreme cases, use of an alcohol swab may help diagnose dermatitis neglecta or terra firma-forme dermatosis by completely removing any pigmentation.4 

After surgery, the alcohol swab can remove skin marker(s) and blood and prepare the site for the surgical dressing. There also is some evidence to suggest that cleansing the surgical site with an alcohol swab as part of routine postoperative wound care may decrease incidence of surgical-site infection.5 At follow-up, the swab can remove crust and clean the skin before suture removal. If infection is suspected, the swab can cleanse skin before a wound culture is obtained to remove skin commensals and flora on the outer surface of the wound.

Practice Implications

The 70% isopropyl alcohol swab can assist the dermatologist in numerous tasks related to everyday procedures. It is readily available in every clinic and costs only a few cents.

References
  1. Pollock JR, Chen JY, Dorius DA, et al. Decreasing physician Medicare reimbursement for dermatology services. J Am Acad Dermatol. 2022;86:1154-1156.
  2. Thomas CJ, Elston DM. Medical pearl: Gentian violet to highlight the cornoid lamella in disseminated superficial actinic porokeratosis.J Am Acad Dermatol. 2005;52(3 pt 1):513-514.
  3. Kelly SC, Purcell SM. Prevention of nosocomial infection during dermoscopy? Dermatol Surg. 2006;32:552-555.
  4. Blattner CM, Perry B, Snider K, et al. Clinical pearl: increasing utility of isopropyl alcohol for cutaneous dyschromia. Cutis. 2016;97:287;301.
  5. Vogt KN, Chadi S, Parry N, et al. Daily incision cleansing with alcohol reduces the rate of surgical site infections: a pilot study. Am Surg. 2015;81:1182-1186.
References
  1. Pollock JR, Chen JY, Dorius DA, et al. Decreasing physician Medicare reimbursement for dermatology services. J Am Acad Dermatol. 2022;86:1154-1156.
  2. Thomas CJ, Elston DM. Medical pearl: Gentian violet to highlight the cornoid lamella in disseminated superficial actinic porokeratosis.J Am Acad Dermatol. 2005;52(3 pt 1):513-514.
  3. Kelly SC, Purcell SM. Prevention of nosocomial infection during dermoscopy? Dermatol Surg. 2006;32:552-555.
  4. Blattner CM, Perry B, Snider K, et al. Clinical pearl: increasing utility of isopropyl alcohol for cutaneous dyschromia. Cutis. 2016;97:287;301.
  5. Vogt KN, Chadi S, Parry N, et al. Daily incision cleansing with alcohol reduces the rate of surgical site infections: a pilot study. Am Surg. 2015;81:1182-1186.
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Blood Glucose Testing Lancet and Paper Clip as a Milia Extractor

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Blood Glucose Testing Lancet and Paper Clip as a Milia Extractor

Practice Gap

In low-resource settings, dermatologists may not have the preferred tools to evaluate a patient or perform a procedure. Commonplace affordable supplies can be substituted when needed.

Traditionally, tools readily available for comedone extraction in dermatology clinics include sterile disposable hypodermic needles to open the skin and either a comedone extractor or 2 cotton-tip applicators to apply pressure for extraction. However, when these tools are not available, resourceful techniques have been utilized. Ashique and Srinivas1 described a less-painful method for extracting conchae comedones that they called “pen punching,” which involved using the rim of the tip of a ballpoint pen to apply pressure to extract lesions. Mukhtar and Gupta2 used a 3-mL disposable syringe as a comedone extractor; the syringe was cut at the needle hub using a surgical blade, with one half at 30° to 45°. Kaya et al3 used sharp-tipped cautery to puncture closed macrocomedones. Cvancara and Meffert4 described how an autoclaved paper clip could be fashioned into a disposable comedone extractor, highlighting its potential use in humanitarian work or military deployments. A sterilized safety pin has been demonstrated to be an inexpensive tool to extract open and closed comedones without a surgical blade.5 We describe the use of a blood glucose testing lancet and a paper clip for comedone extraction.

Tools and Technique

A patient presented to a satellite clinic requesting extraction of multiple bothersome milia. A comedone extractor was unavailable at that location, and the patient’s access to care elsewhere was limited.

To perform extraction of milia in this case, we used a sterile, twist-top, stainless steel, 30-gauge blood glucose testing lancet and a paper clip sterilized with an isopropyl alcohol wipe (Figure). The beveled edge of the lancet was used to make a superficial opening to the skin, and the end loop of the paper clip was used as a comedone extractor. Applying moderate vertical pressure, 15 milia were expressed from the forearms. The patient tolerated the procedure well and reported minimal pain.

Paper clip and blood glucose testing lancet used for milia extraction.
Paper clip and blood glucose testing lancet used for milia extraction.

Practical Implications

The cost of the paper clip and lancet for our technique was $0.07. These materials are affordable, easy to use, and readily found in a variety of settings, making them a feasible option for performing this procedure. 

References
  1. Ashique KT, Srinivas CR. Pen punching: an innovative technique for comedone extraction from the well of the concha. J Am Acad Dermatol. 2015;73:E177. doi:10.1016/j.jaad.2015.07.033
  2. Mukhtar M, Gupta S. Surgical pearl: disposable syringe as modified customized comedone extractor. J Cutan Aesthet Surg. 2022;15:185-186. doi:10.4103/JCAS.JCAS_112_21
  3. Kaya TI, Tursen U, Kokturk A, et al. An effective extraction technique for the treatment of closed macrocomedones. Dermatol Surg. 2003;29:741-744. doi:10.1046/j.1524-4725.2003.29190.x
  4. Cvancara JL, Meffert JJ. Surgical pearl: versatile paper clip comedo extractor for acne surgery. J Am Acad Dermatol. 1999;40:477-478. doi:10.1016/s0190-9622(99)70501-3
  5. Mukhtar M, Sharma R. Surgical pearl: the safety pin as a better alternative to the versatile paper clip comedo extractor. Int J Dermatol. 2004;43:967-968. doi:10.1111/j.1365-4632.2004.02293.x
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From the Department of Dermatology, University of Texas at Austin Dell Medical School.

The authors report no conflict of interest.

Correspondence: Courtney N. Haller, MD, Health Transformation Building, The University of Texas at Austin, 1601 Trinity St, Building A, Austin, TX 78712 (Courtney.haller@austin.utexas.edu).

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Correspondence: Courtney N. Haller, MD, Health Transformation Building, The University of Texas at Austin, 1601 Trinity St, Building A, Austin, TX 78712 (Courtney.haller@austin.utexas.edu).

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From the Department of Dermatology, University of Texas at Austin Dell Medical School.

The authors report no conflict of interest.

Correspondence: Courtney N. Haller, MD, Health Transformation Building, The University of Texas at Austin, 1601 Trinity St, Building A, Austin, TX 78712 (Courtney.haller@austin.utexas.edu).

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Practice Gap

In low-resource settings, dermatologists may not have the preferred tools to evaluate a patient or perform a procedure. Commonplace affordable supplies can be substituted when needed.

Traditionally, tools readily available for comedone extraction in dermatology clinics include sterile disposable hypodermic needles to open the skin and either a comedone extractor or 2 cotton-tip applicators to apply pressure for extraction. However, when these tools are not available, resourceful techniques have been utilized. Ashique and Srinivas1 described a less-painful method for extracting conchae comedones that they called “pen punching,” which involved using the rim of the tip of a ballpoint pen to apply pressure to extract lesions. Mukhtar and Gupta2 used a 3-mL disposable syringe as a comedone extractor; the syringe was cut at the needle hub using a surgical blade, with one half at 30° to 45°. Kaya et al3 used sharp-tipped cautery to puncture closed macrocomedones. Cvancara and Meffert4 described how an autoclaved paper clip could be fashioned into a disposable comedone extractor, highlighting its potential use in humanitarian work or military deployments. A sterilized safety pin has been demonstrated to be an inexpensive tool to extract open and closed comedones without a surgical blade.5 We describe the use of a blood glucose testing lancet and a paper clip for comedone extraction.

Tools and Technique

A patient presented to a satellite clinic requesting extraction of multiple bothersome milia. A comedone extractor was unavailable at that location, and the patient’s access to care elsewhere was limited.

To perform extraction of milia in this case, we used a sterile, twist-top, stainless steel, 30-gauge blood glucose testing lancet and a paper clip sterilized with an isopropyl alcohol wipe (Figure). The beveled edge of the lancet was used to make a superficial opening to the skin, and the end loop of the paper clip was used as a comedone extractor. Applying moderate vertical pressure, 15 milia were expressed from the forearms. The patient tolerated the procedure well and reported minimal pain.

Paper clip and blood glucose testing lancet used for milia extraction.
Paper clip and blood glucose testing lancet used for milia extraction.

Practical Implications

The cost of the paper clip and lancet for our technique was $0.07. These materials are affordable, easy to use, and readily found in a variety of settings, making them a feasible option for performing this procedure. 

Practice Gap

In low-resource settings, dermatologists may not have the preferred tools to evaluate a patient or perform a procedure. Commonplace affordable supplies can be substituted when needed.

Traditionally, tools readily available for comedone extraction in dermatology clinics include sterile disposable hypodermic needles to open the skin and either a comedone extractor or 2 cotton-tip applicators to apply pressure for extraction. However, when these tools are not available, resourceful techniques have been utilized. Ashique and Srinivas1 described a less-painful method for extracting conchae comedones that they called “pen punching,” which involved using the rim of the tip of a ballpoint pen to apply pressure to extract lesions. Mukhtar and Gupta2 used a 3-mL disposable syringe as a comedone extractor; the syringe was cut at the needle hub using a surgical blade, with one half at 30° to 45°. Kaya et al3 used sharp-tipped cautery to puncture closed macrocomedones. Cvancara and Meffert4 described how an autoclaved paper clip could be fashioned into a disposable comedone extractor, highlighting its potential use in humanitarian work or military deployments. A sterilized safety pin has been demonstrated to be an inexpensive tool to extract open and closed comedones without a surgical blade.5 We describe the use of a blood glucose testing lancet and a paper clip for comedone extraction.

Tools and Technique

A patient presented to a satellite clinic requesting extraction of multiple bothersome milia. A comedone extractor was unavailable at that location, and the patient’s access to care elsewhere was limited.

To perform extraction of milia in this case, we used a sterile, twist-top, stainless steel, 30-gauge blood glucose testing lancet and a paper clip sterilized with an isopropyl alcohol wipe (Figure). The beveled edge of the lancet was used to make a superficial opening to the skin, and the end loop of the paper clip was used as a comedone extractor. Applying moderate vertical pressure, 15 milia were expressed from the forearms. The patient tolerated the procedure well and reported minimal pain.

Paper clip and blood glucose testing lancet used for milia extraction.
Paper clip and blood glucose testing lancet used for milia extraction.

Practical Implications

The cost of the paper clip and lancet for our technique was $0.07. These materials are affordable, easy to use, and readily found in a variety of settings, making them a feasible option for performing this procedure. 

References
  1. Ashique KT, Srinivas CR. Pen punching: an innovative technique for comedone extraction from the well of the concha. J Am Acad Dermatol. 2015;73:E177. doi:10.1016/j.jaad.2015.07.033
  2. Mukhtar M, Gupta S. Surgical pearl: disposable syringe as modified customized comedone extractor. J Cutan Aesthet Surg. 2022;15:185-186. doi:10.4103/JCAS.JCAS_112_21
  3. Kaya TI, Tursen U, Kokturk A, et al. An effective extraction technique for the treatment of closed macrocomedones. Dermatol Surg. 2003;29:741-744. doi:10.1046/j.1524-4725.2003.29190.x
  4. Cvancara JL, Meffert JJ. Surgical pearl: versatile paper clip comedo extractor for acne surgery. J Am Acad Dermatol. 1999;40:477-478. doi:10.1016/s0190-9622(99)70501-3
  5. Mukhtar M, Sharma R. Surgical pearl: the safety pin as a better alternative to the versatile paper clip comedo extractor. Int J Dermatol. 2004;43:967-968. doi:10.1111/j.1365-4632.2004.02293.x
References
  1. Ashique KT, Srinivas CR. Pen punching: an innovative technique for comedone extraction from the well of the concha. J Am Acad Dermatol. 2015;73:E177. doi:10.1016/j.jaad.2015.07.033
  2. Mukhtar M, Gupta S. Surgical pearl: disposable syringe as modified customized comedone extractor. J Cutan Aesthet Surg. 2022;15:185-186. doi:10.4103/JCAS.JCAS_112_21
  3. Kaya TI, Tursen U, Kokturk A, et al. An effective extraction technique for the treatment of closed macrocomedones. Dermatol Surg. 2003;29:741-744. doi:10.1046/j.1524-4725.2003.29190.x
  4. Cvancara JL, Meffert JJ. Surgical pearl: versatile paper clip comedo extractor for acne surgery. J Am Acad Dermatol. 1999;40:477-478. doi:10.1016/s0190-9622(99)70501-3
  5. Mukhtar M, Sharma R. Surgical pearl: the safety pin as a better alternative to the versatile paper clip comedo extractor. Int J Dermatol. 2004;43:967-968. doi:10.1111/j.1365-4632.2004.02293.x
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Suture Selection to Minimize Postoperative Postinflammatory Hyperpigmentation in Patients With Skin of Color During Mohs Micrographic Surgery

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Practice Gap

Proper suture selection is imperative for appropriate wound healing to minimize the risk for infection and inflammation and to reduce scarring. In Mohs micrographic surgery (MMS), suture selection should be given high consideration in patients with skin of color.1 Using the right type of suture and wound closure technique can lead to favorable aesthetic outcomes by preventing postoperative postinflammatory hyperpigmentation (PIH) and keloids. Data on the choice of suture material in patients with skin of color are limited.

Suture selection depends on a variety of factors including but not limited to the location of the wound on the body, risk for infection, cost, availability, and the personal preference and experience of the MMS surgeon. During the COVID-19 pandemic, suturepreference among dermatologic surgeons shifted to fast-absorbing gut sutures,2 offering alternatives to synthetic monofilament polypropylene and nylon sutures. Absorbable sutures reduced the need for in-person follow-up visits without increasing the incidence of postoperative complications.

Despite these benefits, research suggests that natural absorbable gut sutures induce cutaneous inflammation and should be avoided in patients with skin of color.1,3,4 Nonabsorbable sutures are less reactive, reducing PIH after MMS in patients with skin of color.

Tools and Technique

Use of nonabsorbable stitches is a practical solution to reduce the risk for inflammation in patients with skin of color. Increased inflammation can lead to PIH and increase the risk for keloids in this patient population. Some patients will experience PIH after a surgical procedure regardless of the sutures used to repair the closure; however, one of our goals with patients with skin of color undergoing MMS is to reduce the inflammatory risk that could lead to PIH to ensure optimal aesthetic outcomes.

A middle-aged African woman with darker skin and a history of developing PIH after trauma to the skin presented to our clinic for MMS of a dermatofibrosarcoma protuberans on the upper abdomen. We used a simple running suture with 4-0 nylon to close the surgical wound. We avoided fast-absorbing gut sutures because they have high tissue reactivity1,4; use of sutures with low tissue reactivity, such as nylon and polypropylene, decreases the risk for inflammation without compromising alignment of wound edges and overall cosmesis of the repair. Prolene also is cost-effective and presents a decreased risk for wound dehiscence.5 After cauterizing the wound, we placed multiple synthetic absorbable sutures first to close the wound. We then did a double-running suture of nonabsorbable monofilament suture to reapproximate the epidermal edges with minimal tension. We placed 2 sets of running stitches to minimize the risk for dehiscence along the scar.

The patient was required to return for removal of the nonabsorbable sutures; this postoperative visit was covered by health insurance at no additional cost to the patient. In comparison, long-term repeat visits to treat PIH with a laser or chemical peel would have been more costly. Given that treatment of PIH is considered cosmetic, laser treatment would have been priced at several hundred dollars per session at our institution, and the patient would likely have had a copay for a pretreatment lightening cream such as hydroquinone. Our patient had a favorable cosmetic outcome and reported no or minimal evidence of PIH months after the procedure.

Patients should be instructed to apply petrolatum twice daily, use sun-protective clothing, and cover sutures to minimize exposure to the sun and prevent crusting of the wound. Postinflammatory hyperpigmentation can be proactively treated postoperatively with topical hydroquinone, which was not needed in our patient.

 

 

Practice Implications

Although some studies suggest that there are no cosmetic differences between absorbable and nonabsorbable sutures, the effect of suture type in patients with skin of color undergoing MMS often is unreported or is not studied.6,7 The high reactivity and cutaneous inflammation associated with absorbable gut sutures are important considerations in this patient population.

In patients with skin of color undergoing MMS, we use nonabsorbable epidermal sutures such as nylon and Prolene because of their low reactivity and association with favorable aesthetic outcomes. Nonabsorbable sutures can be safely used in patients of all ages who are undergoing MMS under local anesthesia.

An exception would be the use of the absorbable suture Monocryl (J&J MedTech) in patients with skin of color who need a running subcuticular wound closure because it has low tissue reactivity and maintains high tensile strength. Monocryl has been shown to create less-reactive scars, which decreases the risk for keloids.8,9

More clinical studies are needed to assess the increased susceptibility to PIH in patients with skin of color when using absorbable gut sutures.

References
  1. Williams R, Ciocon D. Mohs micrographic surgery in skin of color. J Drugs Dermatol. 2022;21:536-541. doi:10.36849/JDD.6469
  2. Gallop J, Andrasik W, Lucas J. Successful use of percutaneous dissolvable sutures during COVID-19 pandemic: a retrospective review. J Cutan Med Surg. 2023;27:34-38. doi:10.1177/12034754221143083
  3. Byrne M, Aly A. The surgical suture. Aesthet Surg J. 2019;39(suppl 2):S67-S72. doi:10.1093/asj/sjz036
  4. Koppa M, House R, Tobin V, et al. Suture material choice can increase risk of hypersensitivity in hand trauma patients. Eur J Plast Surg. 2023;46:239-243. doi:10.1007/s00238-022-01986-7
  5. Pandey S, Singh M, Singh K, et al. A prospective randomized study comparing non-absorbable polypropylene (Prolene®) and delayed absorbable polyglactin 910 (Vicryl®) suture material in mass closure of vertical laparotomy wounds. Indian J Surg. 2013;75:306-310. doi:10.1007/s12262-012-0492-x
  6. Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg. 2003;5:488-490. doi:10.1001/archfaci.5.6.488
  7. Kim J, Singh Maan H, Cool AJ, et al. Fast absorbing gut suture versus cyanoacrylate tissue adhesive in the epidermal closure of linear repairs following Mohs micrographic surgery. J Clin Aesthet Dermatol. 2015;8:24-29.
  8. Niessen FB, Spauwen PH, Kon M. The role of suture material in hypertrophic scar formation: Monocryl vs. Vicryl-Rapide. Ann Plast Surg. 1997;39:254-260. doi:10.1097/00000637-199709000-00006
  9. Fosko SW, Heap D. Surgical pearl: an economical means of skin closure with absorbable suture. J Am Acad Dermatol. 1998;39(2 pt 1):248-250. doi:10.1016/s0190-9622(98)70084-2
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Carolina Gonzalez Bravo is from the Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City. Dr. Negbenebor is from the Department of Dermatology, University of Iowa Hospitals & Clinics, Iowa City.

Carolina Gonzalez Bravo reports no conflict of interest. Dr. Negbenebor has served as a speaker for Nema Beauty Cosmetics.

Correspondence: Nicole A. Negbenebor, MD, 200 Hawkins Dr, Iowa City, IA 52242 (nicole-negbenebor@uiowa.edu).

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Carolina Gonzalez Bravo reports no conflict of interest. Dr. Negbenebor has served as a speaker for Nema Beauty Cosmetics.

Correspondence: Nicole A. Negbenebor, MD, 200 Hawkins Dr, Iowa City, IA 52242 (nicole-negbenebor@uiowa.edu).

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Carolina Gonzalez Bravo is from the Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City. Dr. Negbenebor is from the Department of Dermatology, University of Iowa Hospitals & Clinics, Iowa City.

Carolina Gonzalez Bravo reports no conflict of interest. Dr. Negbenebor has served as a speaker for Nema Beauty Cosmetics.

Correspondence: Nicole A. Negbenebor, MD, 200 Hawkins Dr, Iowa City, IA 52242 (nicole-negbenebor@uiowa.edu).

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Practice Gap

Proper suture selection is imperative for appropriate wound healing to minimize the risk for infection and inflammation and to reduce scarring. In Mohs micrographic surgery (MMS), suture selection should be given high consideration in patients with skin of color.1 Using the right type of suture and wound closure technique can lead to favorable aesthetic outcomes by preventing postoperative postinflammatory hyperpigmentation (PIH) and keloids. Data on the choice of suture material in patients with skin of color are limited.

Suture selection depends on a variety of factors including but not limited to the location of the wound on the body, risk for infection, cost, availability, and the personal preference and experience of the MMS surgeon. During the COVID-19 pandemic, suturepreference among dermatologic surgeons shifted to fast-absorbing gut sutures,2 offering alternatives to synthetic monofilament polypropylene and nylon sutures. Absorbable sutures reduced the need for in-person follow-up visits without increasing the incidence of postoperative complications.

Despite these benefits, research suggests that natural absorbable gut sutures induce cutaneous inflammation and should be avoided in patients with skin of color.1,3,4 Nonabsorbable sutures are less reactive, reducing PIH after MMS in patients with skin of color.

Tools and Technique

Use of nonabsorbable stitches is a practical solution to reduce the risk for inflammation in patients with skin of color. Increased inflammation can lead to PIH and increase the risk for keloids in this patient population. Some patients will experience PIH after a surgical procedure regardless of the sutures used to repair the closure; however, one of our goals with patients with skin of color undergoing MMS is to reduce the inflammatory risk that could lead to PIH to ensure optimal aesthetic outcomes.

A middle-aged African woman with darker skin and a history of developing PIH after trauma to the skin presented to our clinic for MMS of a dermatofibrosarcoma protuberans on the upper abdomen. We used a simple running suture with 4-0 nylon to close the surgical wound. We avoided fast-absorbing gut sutures because they have high tissue reactivity1,4; use of sutures with low tissue reactivity, such as nylon and polypropylene, decreases the risk for inflammation without compromising alignment of wound edges and overall cosmesis of the repair. Prolene also is cost-effective and presents a decreased risk for wound dehiscence.5 After cauterizing the wound, we placed multiple synthetic absorbable sutures first to close the wound. We then did a double-running suture of nonabsorbable monofilament suture to reapproximate the epidermal edges with minimal tension. We placed 2 sets of running stitches to minimize the risk for dehiscence along the scar.

The patient was required to return for removal of the nonabsorbable sutures; this postoperative visit was covered by health insurance at no additional cost to the patient. In comparison, long-term repeat visits to treat PIH with a laser or chemical peel would have been more costly. Given that treatment of PIH is considered cosmetic, laser treatment would have been priced at several hundred dollars per session at our institution, and the patient would likely have had a copay for a pretreatment lightening cream such as hydroquinone. Our patient had a favorable cosmetic outcome and reported no or minimal evidence of PIH months after the procedure.

Patients should be instructed to apply petrolatum twice daily, use sun-protective clothing, and cover sutures to minimize exposure to the sun and prevent crusting of the wound. Postinflammatory hyperpigmentation can be proactively treated postoperatively with topical hydroquinone, which was not needed in our patient.

 

 

Practice Implications

Although some studies suggest that there are no cosmetic differences between absorbable and nonabsorbable sutures, the effect of suture type in patients with skin of color undergoing MMS often is unreported or is not studied.6,7 The high reactivity and cutaneous inflammation associated with absorbable gut sutures are important considerations in this patient population.

In patients with skin of color undergoing MMS, we use nonabsorbable epidermal sutures such as nylon and Prolene because of their low reactivity and association with favorable aesthetic outcomes. Nonabsorbable sutures can be safely used in patients of all ages who are undergoing MMS under local anesthesia.

An exception would be the use of the absorbable suture Monocryl (J&J MedTech) in patients with skin of color who need a running subcuticular wound closure because it has low tissue reactivity and maintains high tensile strength. Monocryl has been shown to create less-reactive scars, which decreases the risk for keloids.8,9

More clinical studies are needed to assess the increased susceptibility to PIH in patients with skin of color when using absorbable gut sutures.

Practice Gap

Proper suture selection is imperative for appropriate wound healing to minimize the risk for infection and inflammation and to reduce scarring. In Mohs micrographic surgery (MMS), suture selection should be given high consideration in patients with skin of color.1 Using the right type of suture and wound closure technique can lead to favorable aesthetic outcomes by preventing postoperative postinflammatory hyperpigmentation (PIH) and keloids. Data on the choice of suture material in patients with skin of color are limited.

Suture selection depends on a variety of factors including but not limited to the location of the wound on the body, risk for infection, cost, availability, and the personal preference and experience of the MMS surgeon. During the COVID-19 pandemic, suturepreference among dermatologic surgeons shifted to fast-absorbing gut sutures,2 offering alternatives to synthetic monofilament polypropylene and nylon sutures. Absorbable sutures reduced the need for in-person follow-up visits without increasing the incidence of postoperative complications.

Despite these benefits, research suggests that natural absorbable gut sutures induce cutaneous inflammation and should be avoided in patients with skin of color.1,3,4 Nonabsorbable sutures are less reactive, reducing PIH after MMS in patients with skin of color.

Tools and Technique

Use of nonabsorbable stitches is a practical solution to reduce the risk for inflammation in patients with skin of color. Increased inflammation can lead to PIH and increase the risk for keloids in this patient population. Some patients will experience PIH after a surgical procedure regardless of the sutures used to repair the closure; however, one of our goals with patients with skin of color undergoing MMS is to reduce the inflammatory risk that could lead to PIH to ensure optimal aesthetic outcomes.

A middle-aged African woman with darker skin and a history of developing PIH after trauma to the skin presented to our clinic for MMS of a dermatofibrosarcoma protuberans on the upper abdomen. We used a simple running suture with 4-0 nylon to close the surgical wound. We avoided fast-absorbing gut sutures because they have high tissue reactivity1,4; use of sutures with low tissue reactivity, such as nylon and polypropylene, decreases the risk for inflammation without compromising alignment of wound edges and overall cosmesis of the repair. Prolene also is cost-effective and presents a decreased risk for wound dehiscence.5 After cauterizing the wound, we placed multiple synthetic absorbable sutures first to close the wound. We then did a double-running suture of nonabsorbable monofilament suture to reapproximate the epidermal edges with minimal tension. We placed 2 sets of running stitches to minimize the risk for dehiscence along the scar.

The patient was required to return for removal of the nonabsorbable sutures; this postoperative visit was covered by health insurance at no additional cost to the patient. In comparison, long-term repeat visits to treat PIH with a laser or chemical peel would have been more costly. Given that treatment of PIH is considered cosmetic, laser treatment would have been priced at several hundred dollars per session at our institution, and the patient would likely have had a copay for a pretreatment lightening cream such as hydroquinone. Our patient had a favorable cosmetic outcome and reported no or minimal evidence of PIH months after the procedure.

Patients should be instructed to apply petrolatum twice daily, use sun-protective clothing, and cover sutures to minimize exposure to the sun and prevent crusting of the wound. Postinflammatory hyperpigmentation can be proactively treated postoperatively with topical hydroquinone, which was not needed in our patient.

 

 

Practice Implications

Although some studies suggest that there are no cosmetic differences between absorbable and nonabsorbable sutures, the effect of suture type in patients with skin of color undergoing MMS often is unreported or is not studied.6,7 The high reactivity and cutaneous inflammation associated with absorbable gut sutures are important considerations in this patient population.

In patients with skin of color undergoing MMS, we use nonabsorbable epidermal sutures such as nylon and Prolene because of their low reactivity and association with favorable aesthetic outcomes. Nonabsorbable sutures can be safely used in patients of all ages who are undergoing MMS under local anesthesia.

An exception would be the use of the absorbable suture Monocryl (J&J MedTech) in patients with skin of color who need a running subcuticular wound closure because it has low tissue reactivity and maintains high tensile strength. Monocryl has been shown to create less-reactive scars, which decreases the risk for keloids.8,9

More clinical studies are needed to assess the increased susceptibility to PIH in patients with skin of color when using absorbable gut sutures.

References
  1. Williams R, Ciocon D. Mohs micrographic surgery in skin of color. J Drugs Dermatol. 2022;21:536-541. doi:10.36849/JDD.6469
  2. Gallop J, Andrasik W, Lucas J. Successful use of percutaneous dissolvable sutures during COVID-19 pandemic: a retrospective review. J Cutan Med Surg. 2023;27:34-38. doi:10.1177/12034754221143083
  3. Byrne M, Aly A. The surgical suture. Aesthet Surg J. 2019;39(suppl 2):S67-S72. doi:10.1093/asj/sjz036
  4. Koppa M, House R, Tobin V, et al. Suture material choice can increase risk of hypersensitivity in hand trauma patients. Eur J Plast Surg. 2023;46:239-243. doi:10.1007/s00238-022-01986-7
  5. Pandey S, Singh M, Singh K, et al. A prospective randomized study comparing non-absorbable polypropylene (Prolene®) and delayed absorbable polyglactin 910 (Vicryl®) suture material in mass closure of vertical laparotomy wounds. Indian J Surg. 2013;75:306-310. doi:10.1007/s12262-012-0492-x
  6. Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg. 2003;5:488-490. doi:10.1001/archfaci.5.6.488
  7. Kim J, Singh Maan H, Cool AJ, et al. Fast absorbing gut suture versus cyanoacrylate tissue adhesive in the epidermal closure of linear repairs following Mohs micrographic surgery. J Clin Aesthet Dermatol. 2015;8:24-29.
  8. Niessen FB, Spauwen PH, Kon M. The role of suture material in hypertrophic scar formation: Monocryl vs. Vicryl-Rapide. Ann Plast Surg. 1997;39:254-260. doi:10.1097/00000637-199709000-00006
  9. Fosko SW, Heap D. Surgical pearl: an economical means of skin closure with absorbable suture. J Am Acad Dermatol. 1998;39(2 pt 1):248-250. doi:10.1016/s0190-9622(98)70084-2
References
  1. Williams R, Ciocon D. Mohs micrographic surgery in skin of color. J Drugs Dermatol. 2022;21:536-541. doi:10.36849/JDD.6469
  2. Gallop J, Andrasik W, Lucas J. Successful use of percutaneous dissolvable sutures during COVID-19 pandemic: a retrospective review. J Cutan Med Surg. 2023;27:34-38. doi:10.1177/12034754221143083
  3. Byrne M, Aly A. The surgical suture. Aesthet Surg J. 2019;39(suppl 2):S67-S72. doi:10.1093/asj/sjz036
  4. Koppa M, House R, Tobin V, et al. Suture material choice can increase risk of hypersensitivity in hand trauma patients. Eur J Plast Surg. 2023;46:239-243. doi:10.1007/s00238-022-01986-7
  5. Pandey S, Singh M, Singh K, et al. A prospective randomized study comparing non-absorbable polypropylene (Prolene®) and delayed absorbable polyglactin 910 (Vicryl®) suture material in mass closure of vertical laparotomy wounds. Indian J Surg. 2013;75:306-310. doi:10.1007/s12262-012-0492-x
  6. Parell GJ, Becker GD. Comparison of absorbable with nonabsorbable sutures in closure of facial skin wounds. Arch Facial Plast Surg. 2003;5:488-490. doi:10.1001/archfaci.5.6.488
  7. Kim J, Singh Maan H, Cool AJ, et al. Fast absorbing gut suture versus cyanoacrylate tissue adhesive in the epidermal closure of linear repairs following Mohs micrographic surgery. J Clin Aesthet Dermatol. 2015;8:24-29.
  8. Niessen FB, Spauwen PH, Kon M. The role of suture material in hypertrophic scar formation: Monocryl vs. Vicryl-Rapide. Ann Plast Surg. 1997;39:254-260. doi:10.1097/00000637-199709000-00006
  9. Fosko SW, Heap D. Surgical pearl: an economical means of skin closure with absorbable suture. J Am Acad Dermatol. 1998;39(2 pt 1):248-250. doi:10.1016/s0190-9622(98)70084-2
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Knead a Hand? Use of a Portable Massager to Reduce Patient Pain and Anxiety During Nail Surgery

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Knead a Hand? Use of a Portable Massager to Reduce Patient Pain and Anxiety During Nail Surgery

Practice Gap

Pain and anxiety are common in fully conscious patients undergoing dermatologic surgery with local anesthesia. Particularly during nail surgery, pain from anesthetic injection—caused by both needle insertion and fluid infiltration—occurs because the nail unit is highly vascularized and innervated.1 Current methods to improve patient comfort during infiltration include use of a buffered anesthetic solution, warming the anesthetic, slower technique, and direct cold application.2

Perioperative anxiety correlates with increased postoperative pain, analgesic use, and delayed recovery. Furthermore, increased perioperative anxiety reduces the pain threshold and elevates estimates of pain intensity.3 Therefore, reducing procedure-related anxiety and pain may improve quality of care and ease patient discomfort.

Distraction is a common and practical nonpharmacotherapeutic technique for reducing pain and anxiety during medical procedures. The refocusing method of distraction aims to divert attention away from pain to more pleasant stimuli to reduce pain perception.3 Several methods of distraction—using stress balls, engaging in conversation, hand-holding, applying virtual reality, and playing videos—can decrease perioperative anxiety and pain.3-6

Procedural pain and distraction techniques have been evaluated in the pediatric population more than in adults.4 Nail surgery–associated pain and distraction techniques for nail surgery have been inadequately studied.7

We offer a distraction technique utilizing a portable massager to ensure that patients are as comfortable as possible when the local anesthetic is injected prior to the first incision.

The Technique

A portable shiatsu massager that uses heat and deep-tissue kneading is placed on the upper thigh for toenail cases or lower arm for fingernail cases during injection of anesthetic to divert the patient’s attention from the surgical site (Figure). Kneading from the massage helps distract the patient from pain by introducing a competing, more pleasant, vibrating sensation that overrides pain signals; the relaxation component helps to diminish patient anxiety during injection.

A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.
A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.

Practice Implications

Use of a portable massager may reduce pain through both distraction and vibration. In a randomized clinical trial of 115 patients undergoing hand or facial surgery, patients who viewed a distraction video during the procedure reported a lower pain score compared to the control group (mean [SD] visual analog scale of pain score, 3.4 [2.6] vs 4.5 [2.6][P=.01]).4 In another randomized clinical trial of 25 patients undergoing lip augmentation, 92% of patients (23/25) in the vibration-assisted arm endorsed less pain during procedures compared to the arm without vibration (mean [SD] pain score, 3.82 [1.73] vs 5.6 [1.76][P<.001]).8

Utilization of a portable massager is a safe means of improving the patient experience; the distracting and relaxing effects and intense pulsations simultaneously reduce anxiety and pain during nail surgery. Controlled clinical trials are needed to evaluate its efficacy in diminishing both anxiety and pain during nail procedures compared to other analgesic methods.

References
  1. Lipner SR. Pain-minimizing strategies for nail surgery. Cutis. 2018;101:76-77.
  2. Ricardo JW, Lipner SR. Air cooling for improved analgesia during local anesthetic infiltration for nail surgery. J Am Acad Dermatol. 2021;84:E231-E232. doi:10.1016/j.jaad.2019.11.032
  3. Hudson BF, Ogden J, Whiteley MS. Randomized controlled trial to compare the effect of simple distraction interventions on pain and anxiety experienced during conscious surgery. Eur J Pain. 2015;19:1447-1455. doi:10.1002/ejp.675
  4. Molleman J, Tielemans JF, Braam MJI, et al. Distraction as a simple and effective method to reduce pain during local anesthesia: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2019;72:1979-1985. doi:10.1016/j.bjps.2019.07.023
  5. Ricardo JW, Lipner SR. Utilization of a stress ball to diminish anxiety during nail surgery. Cutis. 2020;105:294.
  6. Ricardo JW, Lipner SR. Utilizing a sleep mask to reduce patient anxiety during nail surgery. Cutis. 2021;108:36. doi:10.12788/cutis.0285
  7. Ricardo JW, Qiu Y, Lipner SR. Longitudinal perioperative pain assessment in nail surgery. J Am Acad Dermatol. 2022;87:874-876. doi:10.1016/j.jaad.2021.11.042
  8. Guney K, Sezgin B, Yavuzer R. The efficacy of vibration anesthesia on reducing pain levels during lip augmentation: worth the buzz? Aesthet Surg J. 2017;37:1044-1048. doi:10.1093/asj/sjx073
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Jade Conway is from the School of Medicine, New York Medical College, Valhalla. Samantha Jo Albucker is from Tulane University School of Medicine, New Orleans, Louisiana. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York.

The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, 9th Floor, New York, NY 10021 (shl9032@med.cornell.edu).

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Jade Conway is from the School of Medicine, New York Medical College, Valhalla. Samantha Jo Albucker is from Tulane University School of Medicine, New Orleans, Louisiana. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York.

The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, 9th Floor, New York, NY 10021 (shl9032@med.cornell.edu).

Author and Disclosure Information

Jade Conway is from the School of Medicine, New York Medical College, Valhalla. Samantha Jo Albucker is from Tulane University School of Medicine, New Orleans, Louisiana. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York.

The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, 9th Floor, New York, NY 10021 (shl9032@med.cornell.edu).

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Practice Gap

Pain and anxiety are common in fully conscious patients undergoing dermatologic surgery with local anesthesia. Particularly during nail surgery, pain from anesthetic injection—caused by both needle insertion and fluid infiltration—occurs because the nail unit is highly vascularized and innervated.1 Current methods to improve patient comfort during infiltration include use of a buffered anesthetic solution, warming the anesthetic, slower technique, and direct cold application.2

Perioperative anxiety correlates with increased postoperative pain, analgesic use, and delayed recovery. Furthermore, increased perioperative anxiety reduces the pain threshold and elevates estimates of pain intensity.3 Therefore, reducing procedure-related anxiety and pain may improve quality of care and ease patient discomfort.

Distraction is a common and practical nonpharmacotherapeutic technique for reducing pain and anxiety during medical procedures. The refocusing method of distraction aims to divert attention away from pain to more pleasant stimuli to reduce pain perception.3 Several methods of distraction—using stress balls, engaging in conversation, hand-holding, applying virtual reality, and playing videos—can decrease perioperative anxiety and pain.3-6

Procedural pain and distraction techniques have been evaluated in the pediatric population more than in adults.4 Nail surgery–associated pain and distraction techniques for nail surgery have been inadequately studied.7

We offer a distraction technique utilizing a portable massager to ensure that patients are as comfortable as possible when the local anesthetic is injected prior to the first incision.

The Technique

A portable shiatsu massager that uses heat and deep-tissue kneading is placed on the upper thigh for toenail cases or lower arm for fingernail cases during injection of anesthetic to divert the patient’s attention from the surgical site (Figure). Kneading from the massage helps distract the patient from pain by introducing a competing, more pleasant, vibrating sensation that overrides pain signals; the relaxation component helps to diminish patient anxiety during injection.

A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.
A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.

Practice Implications

Use of a portable massager may reduce pain through both distraction and vibration. In a randomized clinical trial of 115 patients undergoing hand or facial surgery, patients who viewed a distraction video during the procedure reported a lower pain score compared to the control group (mean [SD] visual analog scale of pain score, 3.4 [2.6] vs 4.5 [2.6][P=.01]).4 In another randomized clinical trial of 25 patients undergoing lip augmentation, 92% of patients (23/25) in the vibration-assisted arm endorsed less pain during procedures compared to the arm without vibration (mean [SD] pain score, 3.82 [1.73] vs 5.6 [1.76][P<.001]).8

Utilization of a portable massager is a safe means of improving the patient experience; the distracting and relaxing effects and intense pulsations simultaneously reduce anxiety and pain during nail surgery. Controlled clinical trials are needed to evaluate its efficacy in diminishing both anxiety and pain during nail procedures compared to other analgesic methods.

Practice Gap

Pain and anxiety are common in fully conscious patients undergoing dermatologic surgery with local anesthesia. Particularly during nail surgery, pain from anesthetic injection—caused by both needle insertion and fluid infiltration—occurs because the nail unit is highly vascularized and innervated.1 Current methods to improve patient comfort during infiltration include use of a buffered anesthetic solution, warming the anesthetic, slower technique, and direct cold application.2

Perioperative anxiety correlates with increased postoperative pain, analgesic use, and delayed recovery. Furthermore, increased perioperative anxiety reduces the pain threshold and elevates estimates of pain intensity.3 Therefore, reducing procedure-related anxiety and pain may improve quality of care and ease patient discomfort.

Distraction is a common and practical nonpharmacotherapeutic technique for reducing pain and anxiety during medical procedures. The refocusing method of distraction aims to divert attention away from pain to more pleasant stimuli to reduce pain perception.3 Several methods of distraction—using stress balls, engaging in conversation, hand-holding, applying virtual reality, and playing videos—can decrease perioperative anxiety and pain.3-6

Procedural pain and distraction techniques have been evaluated in the pediatric population more than in adults.4 Nail surgery–associated pain and distraction techniques for nail surgery have been inadequately studied.7

We offer a distraction technique utilizing a portable massager to ensure that patients are as comfortable as possible when the local anesthetic is injected prior to the first incision.

The Technique

A portable shiatsu massager that uses heat and deep-tissue kneading is placed on the upper thigh for toenail cases or lower arm for fingernail cases during injection of anesthetic to divert the patient’s attention from the surgical site (Figure). Kneading from the massage helps distract the patient from pain by introducing a competing, more pleasant, vibrating sensation that overrides pain signals; the relaxation component helps to diminish patient anxiety during injection.

A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.
A portable massager is applied on the thigh to provide distraction in a patient who is receiving an anesthetic injection prior to dermatologic surgery on a toenail.

Practice Implications

Use of a portable massager may reduce pain through both distraction and vibration. In a randomized clinical trial of 115 patients undergoing hand or facial surgery, patients who viewed a distraction video during the procedure reported a lower pain score compared to the control group (mean [SD] visual analog scale of pain score, 3.4 [2.6] vs 4.5 [2.6][P=.01]).4 In another randomized clinical trial of 25 patients undergoing lip augmentation, 92% of patients (23/25) in the vibration-assisted arm endorsed less pain during procedures compared to the arm without vibration (mean [SD] pain score, 3.82 [1.73] vs 5.6 [1.76][P<.001]).8

Utilization of a portable massager is a safe means of improving the patient experience; the distracting and relaxing effects and intense pulsations simultaneously reduce anxiety and pain during nail surgery. Controlled clinical trials are needed to evaluate its efficacy in diminishing both anxiety and pain during nail procedures compared to other analgesic methods.

References
  1. Lipner SR. Pain-minimizing strategies for nail surgery. Cutis. 2018;101:76-77.
  2. Ricardo JW, Lipner SR. Air cooling for improved analgesia during local anesthetic infiltration for nail surgery. J Am Acad Dermatol. 2021;84:E231-E232. doi:10.1016/j.jaad.2019.11.032
  3. Hudson BF, Ogden J, Whiteley MS. Randomized controlled trial to compare the effect of simple distraction interventions on pain and anxiety experienced during conscious surgery. Eur J Pain. 2015;19:1447-1455. doi:10.1002/ejp.675
  4. Molleman J, Tielemans JF, Braam MJI, et al. Distraction as a simple and effective method to reduce pain during local anesthesia: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2019;72:1979-1985. doi:10.1016/j.bjps.2019.07.023
  5. Ricardo JW, Lipner SR. Utilization of a stress ball to diminish anxiety during nail surgery. Cutis. 2020;105:294.
  6. Ricardo JW, Lipner SR. Utilizing a sleep mask to reduce patient anxiety during nail surgery. Cutis. 2021;108:36. doi:10.12788/cutis.0285
  7. Ricardo JW, Qiu Y, Lipner SR. Longitudinal perioperative pain assessment in nail surgery. J Am Acad Dermatol. 2022;87:874-876. doi:10.1016/j.jaad.2021.11.042
  8. Guney K, Sezgin B, Yavuzer R. The efficacy of vibration anesthesia on reducing pain levels during lip augmentation: worth the buzz? Aesthet Surg J. 2017;37:1044-1048. doi:10.1093/asj/sjx073
References
  1. Lipner SR. Pain-minimizing strategies for nail surgery. Cutis. 2018;101:76-77.
  2. Ricardo JW, Lipner SR. Air cooling for improved analgesia during local anesthetic infiltration for nail surgery. J Am Acad Dermatol. 2021;84:E231-E232. doi:10.1016/j.jaad.2019.11.032
  3. Hudson BF, Ogden J, Whiteley MS. Randomized controlled trial to compare the effect of simple distraction interventions on pain and anxiety experienced during conscious surgery. Eur J Pain. 2015;19:1447-1455. doi:10.1002/ejp.675
  4. Molleman J, Tielemans JF, Braam MJI, et al. Distraction as a simple and effective method to reduce pain during local anesthesia: a randomized controlled trial. J Plast Reconstr Aesthet Surg. 2019;72:1979-1985. doi:10.1016/j.bjps.2019.07.023
  5. Ricardo JW, Lipner SR. Utilization of a stress ball to diminish anxiety during nail surgery. Cutis. 2020;105:294.
  6. Ricardo JW, Lipner SR. Utilizing a sleep mask to reduce patient anxiety during nail surgery. Cutis. 2021;108:36. doi:10.12788/cutis.0285
  7. Ricardo JW, Qiu Y, Lipner SR. Longitudinal perioperative pain assessment in nail surgery. J Am Acad Dermatol. 2022;87:874-876. doi:10.1016/j.jaad.2021.11.042
  8. Guney K, Sezgin B, Yavuzer R. The efficacy of vibration anesthesia on reducing pain levels during lip augmentation: worth the buzz? Aesthet Surg J. 2017;37:1044-1048. doi:10.1093/asj/sjx073
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Cadaveric Split-Thickness Skin Graft With Partial Guiding Closure for Scalp Defects Extending to the Periosteum

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Cadaveric Split-Thickness Skin Graft With Partial Guiding Closure for Scalp Defects Extending to the Periosteum

Practice Gap

Scalp defects that extend to or below the periosteum often pose a reconstructive conundrum. Secondary-intention healing is challenging without an intact periosteum, and complex rotational flaps are required in these scenarios.1 For a tumor that is at high risk for recurrence or when adjuvant therapy is necessary, tissue distortion of flaps can make monitoring for recurrence difficult. Similarly, for patients in poor health or who are elderly and have substantial skin atrophy, extensive closure may be undesirable or more technically challenging with a higher risk for adverse events. In these scenarios, additional strategies are necessary to optimize wound healing and cosmesis. A cadaveric split-thickness skin graft (STSG) consisting of biologically active tissue can be used to expedite granulation.2

A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.
FIGURE 1. A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.

Technique

Following tumor clearance on the scalp (Figure 1), wide undermining is performed and 3-0 polyglactin 910 epidermal pulley sutures are placed to partially close the defect. A cadaveric STSG is placed over the remaining exposed periosteum and secured under the pulley sutures (Figure 2). The cadaveric STSG is replaced at 1-week intervals. At 4 weeks, sutures typically are removed. The cadaveric STSG is used until the exposed periosteum is fully granulated and the surgeon decides that granulation arrest is unlikely. The wound then heals by unassisted granulation. This approach provides an excellent final cosmetic outcome while avoiding extensive reconstruction (Figure 3).

Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.
FIGURE 2. Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.

Practice Implications

Scalp defects requiring closure are common for dermatologic surgeons. Several techniques to promote tissue granulation in defects that involve exposed periosteum have been reported, including (1) creation of small holes with a scalpel or chisel to access cortical circulation and (2) using laser modalities to stimulate granulation (eg, an erbium:YAG or CO2 laser).3,4 Although direct comparative studies are needed, the cadaveric STSG provides an approach that increases tissue granulation but does not require more invasive techniques or equipment.

Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.
FIGURE 3. Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.

Autologous STSGs need a wound bed and can fail with an exposed periosteum. Furthermore, an autologous STSG that survives may leave an unsightly, hypopigmented, depressed defect. When a defect involves the periosteum and a primary closure or flap is not ideal, a skin substitute may be an option.

Skin substitutes, including cadaveric STSG, generally are classified as bioengineered skin equivalents, amniotic tissue, or cadaveric bioproducts (Table). Unlike autologous grafts, these skin substitutes can provide rapid coverage of the defect and do not require a highly vascularized wound bed.6 They also minimize the inflammatory response and potentially improve the final cosmetic outcome by improving granulation rather than immediate STSG closure creating a step-off in deep wounds.6

Cadaveric STSGs also have been used in nonhealing ulcerations; diabetic foot ulcers; and ulcerations in which muscle, tendon, or bone are exposed, demonstrating induction of wound healing with superior scar quality and skin function.2,7,8 The utility of the cadaveric STSG is further highlighted by its potential to reduce costs9 compared to bioengineered skin substitutes, though considerable variability exists in pricing (Table).

Skin Substitutes for Split-Thickness Skin Grafts

Consider using a cadaveric STSG with a guiding closure in cases in which there is concern for delayed or absent tissue granulation or when monitoring for recurrence is essential.

References
  1. Jibbe A, Tolkachjov SN. An efficient single-layer suture technique for large scalp flaps. J Am Acad Dermatol. 2020;83:E395-E396. doi:10.1016/j.jaad.2019.07.062
  2. Mosti G, Mattaliano V, Magliaro A, et al. Cadaveric skin grafts may greatly increase the healing rate of recalcitrant ulcers when used both alone and in combination with split-thickness skin grafts. Dermatol Surg. 2020;46:169-179. doi:10.1097/dss.0000000000001990
  3. Valesky EM, Vogl T, Kaufmann R, et al. Trepanation or complete removal of the outer table of the calvarium for granulation induction: the erbium:YAG laser as an alternative to the rose head burr. Dermatology. 2015;230:276-281. doi:10.1159/000368749
  4. Drosou A, Trieu D, Goldberg LH. Scalpel-made holes on exposed scalp bone to promote second intention healing. J Am Acad Dermatol. 2014;71:387-388. doi:10.1016/j.jaad.2014.04.020
  5. Centers for Medicare & Medicaid Services. April 2023 ASP Pricing. Accessed August 25, 2023. https://www.cms.gov/medicare/medicare-part-b-drug-average-sales-price/asp-pricing-files
  6. Shores JT, Gabriel A, Gupta S. Skin substitutes and alternatives: a review. Adv Skin Wound Care. 2007;20(9 Pt 1):493-508. doi:10.1097/01.ASW.0000288217.83128.f3
  7. Li X, Meng X, Wang X, et al. Human acellular dermal matrix allograft: a randomized, controlled human trial for the long-term evaluation of patients with extensive burns. Burns. 2015;41:689-699. doi:10.1016/j.burns.2014.12.007
  8. Juhasz I, Kiss B, Lukacs L, et al. Long-term followup of dermal substitution with acellular dermal implant in burns and postburn scar corrections. Dermatol Res Pract. 2010;2010:210150. doi:10.1155/2010/210150
  9. Towler MA, Rush EW, Richardson MK, et al. Randomized, prospective, blinded-enrollment, head-to-head venous leg ulcer healing trial comparing living, bioengineered skin graft substitute (Apligraf) with living, cryopreserved, human skin allograft (TheraSkin). Clin Podiatr Med Surg. 2018;35:357-365. doi:10.1016/j.cpm.2018.02.006
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Dr. Seger is from the Division of Dermatology, University of Kansas Medical Center, Kansas City. Dr. Neill is from Oregon Health & Science University, Portland. Dr. Tolkachjov is from Epiphany Dermatology, Dallas, Texas.

Drs. Seger and Neill report no conflict of interest. Dr. Tolkachjov is a speaker for Misonix (Bioventus).

Correspondence: Edward W. Seger, MD, MS, Division of Dermatology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160 (ed.seger@gmail.com).

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Dr. Seger is from the Division of Dermatology, University of Kansas Medical Center, Kansas City. Dr. Neill is from Oregon Health & Science University, Portland. Dr. Tolkachjov is from Epiphany Dermatology, Dallas, Texas.

Drs. Seger and Neill report no conflict of interest. Dr. Tolkachjov is a speaker for Misonix (Bioventus).

Correspondence: Edward W. Seger, MD, MS, Division of Dermatology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160 (ed.seger@gmail.com).

Author and Disclosure Information

Dr. Seger is from the Division of Dermatology, University of Kansas Medical Center, Kansas City. Dr. Neill is from Oregon Health & Science University, Portland. Dr. Tolkachjov is from Epiphany Dermatology, Dallas, Texas.

Drs. Seger and Neill report no conflict of interest. Dr. Tolkachjov is a speaker for Misonix (Bioventus).

Correspondence: Edward W. Seger, MD, MS, Division of Dermatology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160 (ed.seger@gmail.com).

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Practice Gap

Scalp defects that extend to or below the periosteum often pose a reconstructive conundrum. Secondary-intention healing is challenging without an intact periosteum, and complex rotational flaps are required in these scenarios.1 For a tumor that is at high risk for recurrence or when adjuvant therapy is necessary, tissue distortion of flaps can make monitoring for recurrence difficult. Similarly, for patients in poor health or who are elderly and have substantial skin atrophy, extensive closure may be undesirable or more technically challenging with a higher risk for adverse events. In these scenarios, additional strategies are necessary to optimize wound healing and cosmesis. A cadaveric split-thickness skin graft (STSG) consisting of biologically active tissue can be used to expedite granulation.2

A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.
FIGURE 1. A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.

Technique

Following tumor clearance on the scalp (Figure 1), wide undermining is performed and 3-0 polyglactin 910 epidermal pulley sutures are placed to partially close the defect. A cadaveric STSG is placed over the remaining exposed periosteum and secured under the pulley sutures (Figure 2). The cadaveric STSG is replaced at 1-week intervals. At 4 weeks, sutures typically are removed. The cadaveric STSG is used until the exposed periosteum is fully granulated and the surgeon decides that granulation arrest is unlikely. The wound then heals by unassisted granulation. This approach provides an excellent final cosmetic outcome while avoiding extensive reconstruction (Figure 3).

Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.
FIGURE 2. Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.

Practice Implications

Scalp defects requiring closure are common for dermatologic surgeons. Several techniques to promote tissue granulation in defects that involve exposed periosteum have been reported, including (1) creation of small holes with a scalpel or chisel to access cortical circulation and (2) using laser modalities to stimulate granulation (eg, an erbium:YAG or CO2 laser).3,4 Although direct comparative studies are needed, the cadaveric STSG provides an approach that increases tissue granulation but does not require more invasive techniques or equipment.

Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.
FIGURE 3. Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.

Autologous STSGs need a wound bed and can fail with an exposed periosteum. Furthermore, an autologous STSG that survives may leave an unsightly, hypopigmented, depressed defect. When a defect involves the periosteum and a primary closure or flap is not ideal, a skin substitute may be an option.

Skin substitutes, including cadaveric STSG, generally are classified as bioengineered skin equivalents, amniotic tissue, or cadaveric bioproducts (Table). Unlike autologous grafts, these skin substitutes can provide rapid coverage of the defect and do not require a highly vascularized wound bed.6 They also minimize the inflammatory response and potentially improve the final cosmetic outcome by improving granulation rather than immediate STSG closure creating a step-off in deep wounds.6

Cadaveric STSGs also have been used in nonhealing ulcerations; diabetic foot ulcers; and ulcerations in which muscle, tendon, or bone are exposed, demonstrating induction of wound healing with superior scar quality and skin function.2,7,8 The utility of the cadaveric STSG is further highlighted by its potential to reduce costs9 compared to bioengineered skin substitutes, though considerable variability exists in pricing (Table).

Skin Substitutes for Split-Thickness Skin Grafts

Consider using a cadaveric STSG with a guiding closure in cases in which there is concern for delayed or absent tissue granulation or when monitoring for recurrence is essential.

Practice Gap

Scalp defects that extend to or below the periosteum often pose a reconstructive conundrum. Secondary-intention healing is challenging without an intact periosteum, and complex rotational flaps are required in these scenarios.1 For a tumor that is at high risk for recurrence or when adjuvant therapy is necessary, tissue distortion of flaps can make monitoring for recurrence difficult. Similarly, for patients in poor health or who are elderly and have substantial skin atrophy, extensive closure may be undesirable or more technically challenging with a higher risk for adverse events. In these scenarios, additional strategies are necessary to optimize wound healing and cosmesis. A cadaveric split-thickness skin graft (STSG) consisting of biologically active tissue can be used to expedite granulation.2

A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.
FIGURE 1. A deep scalp defect devoid of periosteum following Mohs micrographic surgery in an elderly patient with immobile adjacent tissue and multiple comorbidities.

Technique

Following tumor clearance on the scalp (Figure 1), wide undermining is performed and 3-0 polyglactin 910 epidermal pulley sutures are placed to partially close the defect. A cadaveric STSG is placed over the remaining exposed periosteum and secured under the pulley sutures (Figure 2). The cadaveric STSG is replaced at 1-week intervals. At 4 weeks, sutures typically are removed. The cadaveric STSG is used until the exposed periosteum is fully granulated and the surgeon decides that granulation arrest is unlikely. The wound then heals by unassisted granulation. This approach provides an excellent final cosmetic outcome while avoiding extensive reconstruction (Figure 3).

Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.
FIGURE 2. Pulley guiding sutures (3-0 polyglactin 910) decrease the size of the defect and secure a cadaveric split-thickness skin graft over the remaining exposed periosteum.

Practice Implications

Scalp defects requiring closure are common for dermatologic surgeons. Several techniques to promote tissue granulation in defects that involve exposed periosteum have been reported, including (1) creation of small holes with a scalpel or chisel to access cortical circulation and (2) using laser modalities to stimulate granulation (eg, an erbium:YAG or CO2 laser).3,4 Although direct comparative studies are needed, the cadaveric STSG provides an approach that increases tissue granulation but does not require more invasive techniques or equipment.

Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.
FIGURE 3. Final cosmetic outcome of a cadaveric split-thickness skin graft at 3 months demonstrating an appropriate wound contour without step-off.

Autologous STSGs need a wound bed and can fail with an exposed periosteum. Furthermore, an autologous STSG that survives may leave an unsightly, hypopigmented, depressed defect. When a defect involves the periosteum and a primary closure or flap is not ideal, a skin substitute may be an option.

Skin substitutes, including cadaveric STSG, generally are classified as bioengineered skin equivalents, amniotic tissue, or cadaveric bioproducts (Table). Unlike autologous grafts, these skin substitutes can provide rapid coverage of the defect and do not require a highly vascularized wound bed.6 They also minimize the inflammatory response and potentially improve the final cosmetic outcome by improving granulation rather than immediate STSG closure creating a step-off in deep wounds.6

Cadaveric STSGs also have been used in nonhealing ulcerations; diabetic foot ulcers; and ulcerations in which muscle, tendon, or bone are exposed, demonstrating induction of wound healing with superior scar quality and skin function.2,7,8 The utility of the cadaveric STSG is further highlighted by its potential to reduce costs9 compared to bioengineered skin substitutes, though considerable variability exists in pricing (Table).

Skin Substitutes for Split-Thickness Skin Grafts

Consider using a cadaveric STSG with a guiding closure in cases in which there is concern for delayed or absent tissue granulation or when monitoring for recurrence is essential.

References
  1. Jibbe A, Tolkachjov SN. An efficient single-layer suture technique for large scalp flaps. J Am Acad Dermatol. 2020;83:E395-E396. doi:10.1016/j.jaad.2019.07.062
  2. Mosti G, Mattaliano V, Magliaro A, et al. Cadaveric skin grafts may greatly increase the healing rate of recalcitrant ulcers when used both alone and in combination with split-thickness skin grafts. Dermatol Surg. 2020;46:169-179. doi:10.1097/dss.0000000000001990
  3. Valesky EM, Vogl T, Kaufmann R, et al. Trepanation or complete removal of the outer table of the calvarium for granulation induction: the erbium:YAG laser as an alternative to the rose head burr. Dermatology. 2015;230:276-281. doi:10.1159/000368749
  4. Drosou A, Trieu D, Goldberg LH. Scalpel-made holes on exposed scalp bone to promote second intention healing. J Am Acad Dermatol. 2014;71:387-388. doi:10.1016/j.jaad.2014.04.020
  5. Centers for Medicare & Medicaid Services. April 2023 ASP Pricing. Accessed August 25, 2023. https://www.cms.gov/medicare/medicare-part-b-drug-average-sales-price/asp-pricing-files
  6. Shores JT, Gabriel A, Gupta S. Skin substitutes and alternatives: a review. Adv Skin Wound Care. 2007;20(9 Pt 1):493-508. doi:10.1097/01.ASW.0000288217.83128.f3
  7. Li X, Meng X, Wang X, et al. Human acellular dermal matrix allograft: a randomized, controlled human trial for the long-term evaluation of patients with extensive burns. Burns. 2015;41:689-699. doi:10.1016/j.burns.2014.12.007
  8. Juhasz I, Kiss B, Lukacs L, et al. Long-term followup of dermal substitution with acellular dermal implant in burns and postburn scar corrections. Dermatol Res Pract. 2010;2010:210150. doi:10.1155/2010/210150
  9. Towler MA, Rush EW, Richardson MK, et al. Randomized, prospective, blinded-enrollment, head-to-head venous leg ulcer healing trial comparing living, bioengineered skin graft substitute (Apligraf) with living, cryopreserved, human skin allograft (TheraSkin). Clin Podiatr Med Surg. 2018;35:357-365. doi:10.1016/j.cpm.2018.02.006
References
  1. Jibbe A, Tolkachjov SN. An efficient single-layer suture technique for large scalp flaps. J Am Acad Dermatol. 2020;83:E395-E396. doi:10.1016/j.jaad.2019.07.062
  2. Mosti G, Mattaliano V, Magliaro A, et al. Cadaveric skin grafts may greatly increase the healing rate of recalcitrant ulcers when used both alone and in combination with split-thickness skin grafts. Dermatol Surg. 2020;46:169-179. doi:10.1097/dss.0000000000001990
  3. Valesky EM, Vogl T, Kaufmann R, et al. Trepanation or complete removal of the outer table of the calvarium for granulation induction: the erbium:YAG laser as an alternative to the rose head burr. Dermatology. 2015;230:276-281. doi:10.1159/000368749
  4. Drosou A, Trieu D, Goldberg LH. Scalpel-made holes on exposed scalp bone to promote second intention healing. J Am Acad Dermatol. 2014;71:387-388. doi:10.1016/j.jaad.2014.04.020
  5. Centers for Medicare & Medicaid Services. April 2023 ASP Pricing. Accessed August 25, 2023. https://www.cms.gov/medicare/medicare-part-b-drug-average-sales-price/asp-pricing-files
  6. Shores JT, Gabriel A, Gupta S. Skin substitutes and alternatives: a review. Adv Skin Wound Care. 2007;20(9 Pt 1):493-508. doi:10.1097/01.ASW.0000288217.83128.f3
  7. Li X, Meng X, Wang X, et al. Human acellular dermal matrix allograft: a randomized, controlled human trial for the long-term evaluation of patients with extensive burns. Burns. 2015;41:689-699. doi:10.1016/j.burns.2014.12.007
  8. Juhasz I, Kiss B, Lukacs L, et al. Long-term followup of dermal substitution with acellular dermal implant in burns and postburn scar corrections. Dermatol Res Pract. 2010;2010:210150. doi:10.1155/2010/210150
  9. Towler MA, Rush EW, Richardson MK, et al. Randomized, prospective, blinded-enrollment, head-to-head venous leg ulcer healing trial comparing living, bioengineered skin graft substitute (Apligraf) with living, cryopreserved, human skin allograft (TheraSkin). Clin Podiatr Med Surg. 2018;35:357-365. doi:10.1016/j.cpm.2018.02.006
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